Loss of cardiomyocyte CYB5R3 impairs redox equilibrium and causes sudden cardiac death

Sudden cardiac death (SCD) in patients with heart failure (HF) is allied with an imbalance in reduction and oxidation (redox) signaling in cardiomyocytes; however, the basic pathways and mechanisms governing redox homeostasis in cardiomyocytes are not fully understood. Here, we show that cytochrome...

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Detalles Bibliográficos
Autores principales: Carew, Nolan T., Schmidt, Heidi M., Yuan, Shuai, Galley, Joseph C., Hall, Robert, Altmann, Helene M., Hahn, Scott A., Miller, Megan P., Wood, Katherine C., Gabris, Bethann, Stapleton, Margaret C., Hartwick, Sean, Fazzari, Marco, Wu, Yijen L., Trebak, Mohamed, Kaufman, Brett A., McTiernan, Charles F., Schopfer, Francisco J., Navas, Placido, Thibodeau, Patrick H., McNamara, Dennis M., Salama, Guy, Straub, Adam C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9479700/
https://www.ncbi.nlm.nih.gov/pubmed/36106636
http://dx.doi.org/10.1172/JCI147120

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