Hepatitis E – epidemiology and clinical course in the largest cohort in the Czech Republic

INTRODUCTION: The majority of hepatitis E (HE) reports come from Western Europe. The aim of the study was to describe the typical epidemiological and clinical characteristics of HE in the Czech Republic. METHODS: A retrospective analysis of 173 patients with HE. RESULTS: At least 90% of cases were a...

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Detalles Bibliográficos
Autores principales: Mihalčin, Matúš, Husova, Libuse, Vasickova, Petra, Bena, Marcel, Husa, Petr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Termedia Publishing House 2022
Materias:
Research Letter
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9479705/
https://www.ncbi.nlm.nih.gov/pubmed/36160330
http://dx.doi.org/10.5114/aoms/152338
Descripción
Sumario:INTRODUCTION: The majority of hepatitis E (HE) reports come from Western Europe. The aim of the study was to describe the typical epidemiological and clinical characteristics of HE in the Czech Republic. METHODS: A retrospective analysis of 173 patients with HE. RESULTS: At least 90% of cases were autochthonous (HEV-3 genotype). Seventeen patients were treated with ribavirin. Five underwent liver transplants because of fulminant HE. We noted neurological symptomatology in 9 cases. Six patients developed chronic HE. CONCLUSIONS: There is a possibility of severe health complications caused by the hepatitis E virus in the Czech Republic.

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