Hepatitis E – epidemiology and clinical course in the largest cohort in the Czech Republic

INTRODUCTION: The majority of hepatitis E (HE) reports come from Western Europe. The aim of the study was to describe the typical epidemiological and clinical characteristics of HE in the Czech Republic. METHODS: A retrospective analysis of 173 patients with HE. RESULTS: At least 90% of cases were a...

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Autores principales: Mihalčin, Matúš, Husova, Libuse, Vasickova, Petra, Bena, Marcel, Husa, Petr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Termedia Publishing House 2022
Materias:
Research Letter
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9479705/
https://www.ncbi.nlm.nih.gov/pubmed/36160330
http://dx.doi.org/10.5114/aoms/152338
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author Mihalčin, Matúš
Husova, Libuse
Vasickova, Petra
Bena, Marcel
Husa, Petr
author_facet Mihalčin, Matúš
Husova, Libuse
Vasickova, Petra
Bena, Marcel
Husa, Petr
author_sort Mihalčin, Matúš
collection PubMed
description INTRODUCTION: The majority of hepatitis E (HE) reports come from Western Europe. The aim of the study was to describe the typical epidemiological and clinical characteristics of HE in the Czech Republic. METHODS: A retrospective analysis of 173 patients with HE. RESULTS: At least 90% of cases were autochthonous (HEV-3 genotype). Seventeen patients were treated with ribavirin. Five underwent liver transplants because of fulminant HE. We noted neurological symptomatology in 9 cases. Six patients developed chronic HE. CONCLUSIONS: There is a possibility of severe health complications caused by the hepatitis E virus in the Czech Republic.
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spelling pubmed-94797052022-09-22 Hepatitis E – epidemiology and clinical course in the largest cohort in the Czech Republic Mihalčin, Matúš Husova, Libuse Vasickova, Petra Bena, Marcel Husa, Petr Arch Med Sci Research Letter INTRODUCTION: The majority of hepatitis E (HE) reports come from Western Europe. The aim of the study was to describe the typical epidemiological and clinical characteristics of HE in the Czech Republic. METHODS: A retrospective analysis of 173 patients with HE. RESULTS: At least 90% of cases were autochthonous (HEV-3 genotype). Seventeen patients were treated with ribavirin. Five underwent liver transplants because of fulminant HE. We noted neurological symptomatology in 9 cases. Six patients developed chronic HE. CONCLUSIONS: There is a possibility of severe health complications caused by the hepatitis E virus in the Czech Republic. Termedia Publishing House 2022-08-30 /pmc/articles/PMC9479705/ /pubmed/36160330 http://dx.doi.org/10.5114/aoms/152338 Text en Copyright: © 2022 Termedia & Banach https://creativecommons.org/licenses/by-nc-sa/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) License, allowing third parties to copy and redistribute the material in any medium or format and to remix, transform, and build upon the material, provided the original work is properly cited and states its license.
spellingShingle Research Letter
Mihalčin, Matúš
Husova, Libuse
Vasickova, Petra
Bena, Marcel
Husa, Petr
Hepatitis E – epidemiology and clinical course in the largest cohort in the Czech Republic
title Hepatitis E – epidemiology and clinical course in the largest cohort in the Czech Republic
title_full Hepatitis E – epidemiology and clinical course in the largest cohort in the Czech Republic
title_fullStr Hepatitis E – epidemiology and clinical course in the largest cohort in the Czech Republic
title_full_unstemmed Hepatitis E – epidemiology and clinical course in the largest cohort in the Czech Republic
title_short Hepatitis E – epidemiology and clinical course in the largest cohort in the Czech Republic
title_sort hepatitis e – epidemiology and clinical course in the largest cohort in the czech republic
topic Research Letter
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9479705/
https://www.ncbi.nlm.nih.gov/pubmed/36160330
http://dx.doi.org/10.5114/aoms/152338
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