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Effective connectivity underlying neural and behavioral components of prism adaptation

Prism adaptation (PA) is a form of visuomotor training that produces both sensorimotor and cognitive aftereffects depending on the direction of the visual displacement. Recently, a neural framework explaining both types of PA-induced aftereffects has been proposed, but direct evidence for it is lack...

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Autores principales: Schintu, Selene, Gotts, Stephen J., Freedberg, Michael, Shomstein, Sarah, Wassermann, Eric M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9479732/
https://www.ncbi.nlm.nih.gov/pubmed/36118425
http://dx.doi.org/10.3389/fpsyg.2022.915260
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author Schintu, Selene
Gotts, Stephen J.
Freedberg, Michael
Shomstein, Sarah
Wassermann, Eric M.
author_facet Schintu, Selene
Gotts, Stephen J.
Freedberg, Michael
Shomstein, Sarah
Wassermann, Eric M.
author_sort Schintu, Selene
collection PubMed
description Prism adaptation (PA) is a form of visuomotor training that produces both sensorimotor and cognitive aftereffects depending on the direction of the visual displacement. Recently, a neural framework explaining both types of PA-induced aftereffects has been proposed, but direct evidence for it is lacking. We employed Structural Equation Modeling (SEM), a form of effective connectivity analysis, to establish directionality among connected nodes of the brain network thought to subserve PA. The findings reveal two distinct network branches: (1) a loop involving connections from the parietal cortices to the right parahippocampal gyrus, and (2) a branch linking the lateral premotor cortex to the parahippocampal gyrus via the cerebellum. Like the sensorimotor aftereffects, the first branch exhibited qualitatively different modulations for left versus right PA, and critically, changes in these connections were correlated with the magnitude of the sensorimotor aftereffects. Like the cognitive aftereffects, changes in the second branch were qualitatively similar for left and right PA, with greater change for left PA and a trend correlation with cognitive aftereffects. These results provide direct evidence that PA is supported by two functionally distinct subnetworks, a parietal–temporal network responsible for sensorimotor aftereffects and a fronto-cerebellar network responsible for cognitive aftereffects.
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spelling pubmed-94797322022-09-17 Effective connectivity underlying neural and behavioral components of prism adaptation Schintu, Selene Gotts, Stephen J. Freedberg, Michael Shomstein, Sarah Wassermann, Eric M. Front Psychol Psychology Prism adaptation (PA) is a form of visuomotor training that produces both sensorimotor and cognitive aftereffects depending on the direction of the visual displacement. Recently, a neural framework explaining both types of PA-induced aftereffects has been proposed, but direct evidence for it is lacking. We employed Structural Equation Modeling (SEM), a form of effective connectivity analysis, to establish directionality among connected nodes of the brain network thought to subserve PA. The findings reveal two distinct network branches: (1) a loop involving connections from the parietal cortices to the right parahippocampal gyrus, and (2) a branch linking the lateral premotor cortex to the parahippocampal gyrus via the cerebellum. Like the sensorimotor aftereffects, the first branch exhibited qualitatively different modulations for left versus right PA, and critically, changes in these connections were correlated with the magnitude of the sensorimotor aftereffects. Like the cognitive aftereffects, changes in the second branch were qualitatively similar for left and right PA, with greater change for left PA and a trend correlation with cognitive aftereffects. These results provide direct evidence that PA is supported by two functionally distinct subnetworks, a parietal–temporal network responsible for sensorimotor aftereffects and a fronto-cerebellar network responsible for cognitive aftereffects. Frontiers Media S.A. 2022-09-02 /pmc/articles/PMC9479732/ /pubmed/36118425 http://dx.doi.org/10.3389/fpsyg.2022.915260 Text en Copyright © 2022 Schintu, Gotts, Freedberg, Shomstein and Wassermann. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Psychology
Schintu, Selene
Gotts, Stephen J.
Freedberg, Michael
Shomstein, Sarah
Wassermann, Eric M.
Effective connectivity underlying neural and behavioral components of prism adaptation
title Effective connectivity underlying neural and behavioral components of prism adaptation
title_full Effective connectivity underlying neural and behavioral components of prism adaptation
title_fullStr Effective connectivity underlying neural and behavioral components of prism adaptation
title_full_unstemmed Effective connectivity underlying neural and behavioral components of prism adaptation
title_short Effective connectivity underlying neural and behavioral components of prism adaptation
title_sort effective connectivity underlying neural and behavioral components of prism adaptation
topic Psychology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9479732/
https://www.ncbi.nlm.nih.gov/pubmed/36118425
http://dx.doi.org/10.3389/fpsyg.2022.915260
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