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ADAR2 enzymes: efficient site-specific RNA editors with gene therapy aspirations

The adenosine deaminase acting on RNA (ADAR) enzymes are essential for neuronal function and innate immune control. ADAR1 RNA editing prevents aberrant activation of antiviral dsRNA sensors through editing of long, double-stranded RNAs (dsRNAs). In this review, we focus on the ADAR2 proteins involve...

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Detalles Bibliográficos
Autores principales:	Hajji, Khadija, Sedmík, Jiří, Cherian, Anna, Amoruso, Damiano, Keegan, Liam P., O'Connell, Mary A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory Press 2022
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9479739/ https://www.ncbi.nlm.nih.gov/pubmed/35863867 http://dx.doi.org/10.1261/rna.079266.122

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