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Moving beyond the T cell synapse for combination neoadjuvant immunotherapy in head and neck cancer

Patients with HPV-unrelated head and neck squamous cell carcinoma (HPV-unrelated HNSCC) show only modest benefit from treatment with PD-1 inhibitors (PD-1i). Targeting transforming growth factor β (TGF-β) may make PD-1i more effective by inducing T cell responses. In this issue of the JCI, Redman et...

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Detalles Bibliográficos
Autores principales:	Bell, R. Bryan, Gough, Michael, Crittenden, Marka, Young, Kristina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Clinical Investigation 2022
Materias:	Commentary
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9479756/ https://www.ncbi.nlm.nih.gov/pubmed/36106641 http://dx.doi.org/10.1172/JCI162733

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