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Suicidal behaviour and cognition: A systematic review with special focus on prefrontal deficits

INTRODUCTION: Suicidal behaviour and cognition: A systematic review with special focus on prefrontal deficits Introduction: Suicide is a major health concern worldwide, thus, identifying risk factors would enable a more comprehensive understanding and prevention of this behaviour. Neuropsychological...

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Autores principales: Fernández-Sevillano, J., González-Pinto, A., Rodríguez-Revuelta, J., Alberich-Mesa, S., González-Blanco, L., Zorrilla-Martínez, I., Velasco, Á., López-Pena, P., Abad-Acebedo, I., Saiz, P.A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9480434/
http://dx.doi.org/10.1192/j.eurpsy.2021.1558
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author Fernández-Sevillano, J.
González-Pinto, A.
Rodríguez-Revuelta, J.
Alberich-Mesa, S.
González-Blanco, L.
Zorrilla-Martínez, I.
Velasco, Á.
López-Pena, P.
Abad-Acebedo, I.
Saiz, P.A.
author_facet Fernández-Sevillano, J.
González-Pinto, A.
Rodríguez-Revuelta, J.
Alberich-Mesa, S.
González-Blanco, L.
Zorrilla-Martínez, I.
Velasco, Á.
López-Pena, P.
Abad-Acebedo, I.
Saiz, P.A.
author_sort Fernández-Sevillano, J.
collection PubMed
description INTRODUCTION: Suicidal behaviour and cognition: A systematic review with special focus on prefrontal deficits Introduction: Suicide is a major health concern worldwide, thus, identifying risk factors would enable a more comprehensive understanding and prevention of this behaviour. Neuropsychological alterations could lead to difficulties in interpreting and managing life events resulting in a higher risk of suicide. OBJECTIVES: Objective: Bibliographic review about the influence of neuropsychological deficits on suicidal behaviour. METHODS: Method: A systematic literature search from 2000 to 2020 was performed in Medline (Pubmed), Web of Science, SciELO Citation Index, PsycInfo, PsycArticles and Cochrane Library databases regarding studies comparing cognition of attempters versus non-attempters that share same psychiatric diagnosis. Results: 1.885 patients diagnosed with an Affective Disorder (n = 1512) and Schizophrenia/ Schizoaffective Disorder (n = 373) were included. RESULTS: In general comparison, attention was found to be clearly dysfunctional. Regarding diagnosis, patients with Schizophrenia and previous history of suicidal behaviour showed a poorer performance in executive function. Patients with current symptoms of an Affective Disorder and a previous history of suicidal attempt had poorer performance in attention and executive function. Similarly, euthymic affective patients with history of suicidal behaviour had worse decision-making, attention and executive function performance compared to euthymic non-attempters. CONCLUSIONS: Patients who have attempted suicide have a poorer neuropsychological functioning than non-attempters with a similar psychiatric disorder in attention and executive function. These alterations increase vulnerability for suicide. CONFLICT OF INTEREST: Jessica Fernández-Sevillano is beneficiary of the Pre-PhD Training Programme of the Basque Government. Dr. Gonzalez-Pinto has received grants and served as consultant, advisor or CME speaker for the following entities: Almirall, AstraZeneca, Bristol-Myers
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spelling pubmed-94804342022-09-29 Suicidal behaviour and cognition: A systematic review with special focus on prefrontal deficits Fernández-Sevillano, J. González-Pinto, A. Rodríguez-Revuelta, J. Alberich-Mesa, S. González-Blanco, L. Zorrilla-Martínez, I. Velasco, Á. López-Pena, P. Abad-Acebedo, I. Saiz, P.A. Eur Psychiatry Abstract INTRODUCTION: Suicidal behaviour and cognition: A systematic review with special focus on prefrontal deficits Introduction: Suicide is a major health concern worldwide, thus, identifying risk factors would enable a more comprehensive understanding and prevention of this behaviour. Neuropsychological alterations could lead to difficulties in interpreting and managing life events resulting in a higher risk of suicide. OBJECTIVES: Objective: Bibliographic review about the influence of neuropsychological deficits on suicidal behaviour. METHODS: Method: A systematic literature search from 2000 to 2020 was performed in Medline (Pubmed), Web of Science, SciELO Citation Index, PsycInfo, PsycArticles and Cochrane Library databases regarding studies comparing cognition of attempters versus non-attempters that share same psychiatric diagnosis. Results: 1.885 patients diagnosed with an Affective Disorder (n = 1512) and Schizophrenia/ Schizoaffective Disorder (n = 373) were included. RESULTS: In general comparison, attention was found to be clearly dysfunctional. Regarding diagnosis, patients with Schizophrenia and previous history of suicidal behaviour showed a poorer performance in executive function. Patients with current symptoms of an Affective Disorder and a previous history of suicidal attempt had poorer performance in attention and executive function. Similarly, euthymic affective patients with history of suicidal behaviour had worse decision-making, attention and executive function performance compared to euthymic non-attempters. CONCLUSIONS: Patients who have attempted suicide have a poorer neuropsychological functioning than non-attempters with a similar psychiatric disorder in attention and executive function. These alterations increase vulnerability for suicide. CONFLICT OF INTEREST: Jessica Fernández-Sevillano is beneficiary of the Pre-PhD Training Programme of the Basque Government. Dr. Gonzalez-Pinto has received grants and served as consultant, advisor or CME speaker for the following entities: Almirall, AstraZeneca, Bristol-Myers Cambridge University Press 2021-08-13 /pmc/articles/PMC9480434/ http://dx.doi.org/10.1192/j.eurpsy.2021.1558 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Abstract
Fernández-Sevillano, J.
González-Pinto, A.
Rodríguez-Revuelta, J.
Alberich-Mesa, S.
González-Blanco, L.
Zorrilla-Martínez, I.
Velasco, Á.
López-Pena, P.
Abad-Acebedo, I.
Saiz, P.A.
Suicidal behaviour and cognition: A systematic review with special focus on prefrontal deficits
title Suicidal behaviour and cognition: A systematic review with special focus on prefrontal deficits
title_full Suicidal behaviour and cognition: A systematic review with special focus on prefrontal deficits
title_fullStr Suicidal behaviour and cognition: A systematic review with special focus on prefrontal deficits
title_full_unstemmed Suicidal behaviour and cognition: A systematic review with special focus on prefrontal deficits
title_short Suicidal behaviour and cognition: A systematic review with special focus on prefrontal deficits
title_sort suicidal behaviour and cognition: a systematic review with special focus on prefrontal deficits
topic Abstract
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9480434/
http://dx.doi.org/10.1192/j.eurpsy.2021.1558
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