A study on biomarkers of sepsis and potential role of procalcitonin and ferritin marker in diagnosis, prognosis and treatment

OBJECTIVES: To evaluate the potential value of serum procalcitonin and serum ferritin levels in patients with clinically suspected and proven sepsis and their comparison with established inflammatory markers like C-reactive protein (CRP) and total leukocyte count. MATERIALS AND METHODS: A total of 6...

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Detalles Bibliográficos
Autores principales: Samuel, Marcella Sherin, Latha, Ragunathan, Kavitha, Kannaiyan, Sivasubramanian, Vithiavathi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9480650/
https://www.ncbi.nlm.nih.gov/pubmed/36119270
http://dx.doi.org/10.4103/jfmpc.jfmpc_1920_21
Descripción
Sumario:OBJECTIVES: To evaluate the potential value of serum procalcitonin and serum ferritin levels in patients with clinically suspected and proven sepsis and their comparison with established inflammatory markers like C-reactive protein (CRP) and total leukocyte count. MATERIALS AND METHODS: A total of 60 clinically suspected cases of sepsis were included in this study and each patient was investigated for serum S. ferritin, procalcitonin, and CRP and blood cultures using the BacT/Alert system. RESULTS: Serum procalcitonin at a cut-off value of >2 ng/ml is a valuable biomarker for early diagnosis in sepsis patients due to bacterial infection and has a greater predictive value than serum ferritin, CRP, or any other biomarkers.

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