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Maternal death due to COVID-19, truth or a myth: A narrative review and experience from a teaching hospital in India
The course of coronavirus disease-2019 (COVID-19) in pregnancy is unpredictable with outcome trends ranging from milder disease with zero mortality to severe forms and deaths in different parts of the world. We did a comprehensive review of the literature to understand maternal deaths due to COVID-1...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer - Medknow
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9480707/ https://www.ncbi.nlm.nih.gov/pubmed/36119197 http://dx.doi.org/10.4103/jfmpc.jfmpc_384_21 |
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author | Sharma, Ritu Seth, Shikha Mishra, Pinky Mishra, Neha Sharma, Rakhee Singh, Monika |
author_facet | Sharma, Ritu Seth, Shikha Mishra, Pinky Mishra, Neha Sharma, Rakhee Singh, Monika |
author_sort | Sharma, Ritu |
collection | PubMed |
description | The course of coronavirus disease-2019 (COVID-19) in pregnancy is unpredictable with outcome trends ranging from milder disease with zero mortality to severe forms and deaths in different parts of the world. We did a comprehensive review of the literature to understand maternal deaths due to COVID-19 in detail. The search was conducted in the PubMed, Embase, and Google Scholar databases, using the keywords “maternal mortality”, “maternal death”, “COVID-19”, “septic shock” and “DIC”. The search included original articles, review articles, case reports published till date. We found varying case fatality rates ranging from 0.1% to 12.9%. There are various predictors of maternal death, notably the presence of symptoms, comorbidities, severe disease with cytokine storm and multi-organ dysfunction. We also report higher maternal deaths from low-resource regions owing to gaps in expected and delivered maternal care. While reviewing our institutional data, we found 3 maternal deaths related to COVID-19 in pregnancy. We discussed our experience at our institute of three COVID-19 related maternal mortalities to add evidence to the present data. Most maternal deaths occurred in postpartum period. Late referral, loss to follow-up and inadequate care were important determinants of maternal mortality. We concluded that pregnancy cases with or without complications must be considered high risk and addressed judiciously beginning from infection prevention, early diagnosis, disease categorization, and multidisciplinary approach of management to prevent morbidity and mortality. We strongly suggest strengthening the health care delivery system to save pregnant women from dying, particularly in low-resource countries. |
format | Online Article Text |
id | pubmed-9480707 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Wolters Kluwer - Medknow |
record_format | MEDLINE/PubMed |
spelling | pubmed-94807072022-09-17 Maternal death due to COVID-19, truth or a myth: A narrative review and experience from a teaching hospital in India Sharma, Ritu Seth, Shikha Mishra, Pinky Mishra, Neha Sharma, Rakhee Singh, Monika J Family Med Prim Care Review Article The course of coronavirus disease-2019 (COVID-19) in pregnancy is unpredictable with outcome trends ranging from milder disease with zero mortality to severe forms and deaths in different parts of the world. We did a comprehensive review of the literature to understand maternal deaths due to COVID-19 in detail. The search was conducted in the PubMed, Embase, and Google Scholar databases, using the keywords “maternal mortality”, “maternal death”, “COVID-19”, “septic shock” and “DIC”. The search included original articles, review articles, case reports published till date. We found varying case fatality rates ranging from 0.1% to 12.9%. There are various predictors of maternal death, notably the presence of symptoms, comorbidities, severe disease with cytokine storm and multi-organ dysfunction. We also report higher maternal deaths from low-resource regions owing to gaps in expected and delivered maternal care. While reviewing our institutional data, we found 3 maternal deaths related to COVID-19 in pregnancy. We discussed our experience at our institute of three COVID-19 related maternal mortalities to add evidence to the present data. Most maternal deaths occurred in postpartum period. Late referral, loss to follow-up and inadequate care were important determinants of maternal mortality. We concluded that pregnancy cases with or without complications must be considered high risk and addressed judiciously beginning from infection prevention, early diagnosis, disease categorization, and multidisciplinary approach of management to prevent morbidity and mortality. We strongly suggest strengthening the health care delivery system to save pregnant women from dying, particularly in low-resource countries. Wolters Kluwer - Medknow 2022-06 2022-06-30 /pmc/articles/PMC9480707/ /pubmed/36119197 http://dx.doi.org/10.4103/jfmpc.jfmpc_384_21 Text en Copyright: © 2022 Journal of Family Medicine and Primary Care https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms. |
spellingShingle | Review Article Sharma, Ritu Seth, Shikha Mishra, Pinky Mishra, Neha Sharma, Rakhee Singh, Monika Maternal death due to COVID-19, truth or a myth: A narrative review and experience from a teaching hospital in India |
title | Maternal death due to COVID-19, truth or a myth: A narrative review and experience from a teaching hospital in India |
title_full | Maternal death due to COVID-19, truth or a myth: A narrative review and experience from a teaching hospital in India |
title_fullStr | Maternal death due to COVID-19, truth or a myth: A narrative review and experience from a teaching hospital in India |
title_full_unstemmed | Maternal death due to COVID-19, truth or a myth: A narrative review and experience from a teaching hospital in India |
title_short | Maternal death due to COVID-19, truth or a myth: A narrative review and experience from a teaching hospital in India |
title_sort | maternal death due to covid-19, truth or a myth: a narrative review and experience from a teaching hospital in india |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9480707/ https://www.ncbi.nlm.nih.gov/pubmed/36119197 http://dx.doi.org/10.4103/jfmpc.jfmpc_384_21 |
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