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To study the association between various levels of cord serum albumin (CSA) and significant neonatal hyperbilirubinemia requiring interventions like phototherapy or exchange transfusion

INTRODUCTION: Hyperbilirubinemia is most common normal physiological phenomenon in neonates affecting almost one third of newborn.it may lead to neuro disability leading to deafness and cerebral palsy which can be prevented if detected and treated as soon as possible. Albumin is produced in seventh...

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Autores principales: Pathak, Apeksha, Siddalingesha, R, Prasad, Kamal N., Kamal, Nibha, Sinha, Archana, Ghosh, Ananya, Singh, Bhuwan K., Kumar, Pankaj, Surekha, R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9480789/
https://www.ncbi.nlm.nih.gov/pubmed/36119320
http://dx.doi.org/10.4103/jfmpc.jfmpc_1450_21
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author Pathak, Apeksha
Siddalingesha, R
Prasad, Kamal N.
Kamal, Nibha
Sinha, Archana
Ghosh, Ananya
Singh, Bhuwan K.
Kumar, Pankaj
Surekha, R
author_facet Pathak, Apeksha
Siddalingesha, R
Prasad, Kamal N.
Kamal, Nibha
Sinha, Archana
Ghosh, Ananya
Singh, Bhuwan K.
Kumar, Pankaj
Surekha, R
author_sort Pathak, Apeksha
collection PubMed
description INTRODUCTION: Hyperbilirubinemia is most common normal physiological phenomenon in neonates affecting almost one third of newborn.it may lead to neuro disability leading to deafness and cerebral palsy which can be prevented if detected and treated as soon as possible. Albumin is produced in seventh week of intrauterine life and it can be measured by cord blood and in this study we can establish serum albumin with neonatal hyperbilirubinemia and can be treated by phototherapy or exchange transfusion. MATERIAL AND METHOD: The study consists of 55 randomly selected eligible term neonates delivered at Rajendra Institute of Medical sciences from March 2019 to August 2020. CONCLUSION: In this study, in term neonates, level of serum albumin in umbilical cord less than 2.8 g/dl has no correlation with occurrence significant hyperbilirubinemia, so a level <2.8 gm/dl of serum albumin in umbilical cord blood can be used as critical value indicator in triaging predict the risk of occurring of significant hyperbilirubinemia in term neonates.level >3.4 gm/dl is considered safe in neonates who are the candidates for early discharge in the absence of other risk factors.
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spelling pubmed-94807892022-09-17 To study the association between various levels of cord serum albumin (CSA) and significant neonatal hyperbilirubinemia requiring interventions like phototherapy or exchange transfusion Pathak, Apeksha Siddalingesha, R Prasad, Kamal N. Kamal, Nibha Sinha, Archana Ghosh, Ananya Singh, Bhuwan K. Kumar, Pankaj Surekha, R J Family Med Prim Care Original Article INTRODUCTION: Hyperbilirubinemia is most common normal physiological phenomenon in neonates affecting almost one third of newborn.it may lead to neuro disability leading to deafness and cerebral palsy which can be prevented if detected and treated as soon as possible. Albumin is produced in seventh week of intrauterine life and it can be measured by cord blood and in this study we can establish serum albumin with neonatal hyperbilirubinemia and can be treated by phototherapy or exchange transfusion. MATERIAL AND METHOD: The study consists of 55 randomly selected eligible term neonates delivered at Rajendra Institute of Medical sciences from March 2019 to August 2020. CONCLUSION: In this study, in term neonates, level of serum albumin in umbilical cord less than 2.8 g/dl has no correlation with occurrence significant hyperbilirubinemia, so a level <2.8 gm/dl of serum albumin in umbilical cord blood can be used as critical value indicator in triaging predict the risk of occurring of significant hyperbilirubinemia in term neonates.level >3.4 gm/dl is considered safe in neonates who are the candidates for early discharge in the absence of other risk factors. Wolters Kluwer - Medknow 2022-06 2022-06-30 /pmc/articles/PMC9480789/ /pubmed/36119320 http://dx.doi.org/10.4103/jfmpc.jfmpc_1450_21 Text en Copyright: © 2022 Journal of Family Medicine and Primary Care https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Original Article
Pathak, Apeksha
Siddalingesha, R
Prasad, Kamal N.
Kamal, Nibha
Sinha, Archana
Ghosh, Ananya
Singh, Bhuwan K.
Kumar, Pankaj
Surekha, R
To study the association between various levels of cord serum albumin (CSA) and significant neonatal hyperbilirubinemia requiring interventions like phototherapy or exchange transfusion
title To study the association between various levels of cord serum albumin (CSA) and significant neonatal hyperbilirubinemia requiring interventions like phototherapy or exchange transfusion
title_full To study the association between various levels of cord serum albumin (CSA) and significant neonatal hyperbilirubinemia requiring interventions like phototherapy or exchange transfusion
title_fullStr To study the association between various levels of cord serum albumin (CSA) and significant neonatal hyperbilirubinemia requiring interventions like phototherapy or exchange transfusion
title_full_unstemmed To study the association between various levels of cord serum albumin (CSA) and significant neonatal hyperbilirubinemia requiring interventions like phototherapy or exchange transfusion
title_short To study the association between various levels of cord serum albumin (CSA) and significant neonatal hyperbilirubinemia requiring interventions like phototherapy or exchange transfusion
title_sort to study the association between various levels of cord serum albumin (csa) and significant neonatal hyperbilirubinemia requiring interventions like phototherapy or exchange transfusion
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9480789/
https://www.ncbi.nlm.nih.gov/pubmed/36119320
http://dx.doi.org/10.4103/jfmpc.jfmpc_1450_21
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