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Yeast ORC sumoylation status fine-tunes origin licensing

Sumoylation is emerging as a posttranslation modification important for regulating chromosome duplication and stability. The origin recognition complex (ORC) that directs DNA replication initiation by loading the MCM replicative helicase onto origins is sumoylated in both yeast and human cells. Howe...

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Detalles Bibliográficos
Autores principales:	Regan-Mochrie, Gemma, Hoggard, Timothy, Bhagwat, Nikhil, Lynch, Gerard, Hunter, Neil, Remus, Dirk, Fox, Catherine A., Zhao, Xiaolan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory Press 2022
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9480853/ https://www.ncbi.nlm.nih.gov/pubmed/35926881 http://dx.doi.org/10.1101/gad.349610.122

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