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RNA Pol II pausing facilitates phased pluripotency transitions by buffering transcription

Promoter-proximal RNA Pol II pausing is a critical step in transcriptional control. Pol II pausing has been predominantly studied in tissue culture systems. While Pol II pausing has been shown to be required for mammalian development, the phenotypic and mechanistic details of this requirement are un...

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Detalles Bibliográficos
Autores principales:	Abuhashem, Abderhman, Chivu, Alexandra G., Zhao, Yixin, Rice, Edward J., Siepel, Adam, Danko, Charles G., Hadjantonakis, Anna-Katerina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory Press 2022
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9480856/ https://www.ncbi.nlm.nih.gov/pubmed/35981753 http://dx.doi.org/10.1101/gad.349565.122

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