Apremilast exerts protective effects on stroke outcomes and blood–brain barrier (BBB) dysfunction through regulating Rho‐associated protein kinase 2 expression

AIMS: Stroke is a devastating event and a huge public health concern worldwide. Apremilast (APR) is a selective inhibitor of phosphodiesterase‐4 involved in various neurological diseases, including stroke. However, the protective effects of APR on stroke have not been investigated. Here, we explored...

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Detalles Bibliográficos
Autores principales: Wang, Mingyuan, Meng, Xiangyuan, Cheng, Zhihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9480930/
https://www.ncbi.nlm.nih.gov/pubmed/35971637
http://dx.doi.org/10.1002/brb3.2677

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9480930/
https://www.ncbi.nlm.nih.gov/pubmed/35971637
http://dx.doi.org/10.1002/brb3.2677

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