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A review of stem cell therapy: An emerging treatment for dementia in Alzheimer's and Parkinson's disease
AIM: This article aims to study the benefits and disadvantages of stem cell therapy, especially for patients who have dementia. METHODS: The databases PubMed, Google Scholar, and the National Library of Medicine were searched for literature. All papers on Alzheimer's disease, Lewy body dementia...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9480940/ https://www.ncbi.nlm.nih.gov/pubmed/35971625 http://dx.doi.org/10.1002/brb3.2740 |
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author | Pradhan, Aishwarya Umesh Uwishema, Olivier Onyeaka, Helen Adanur, Irem Dost, Burhan |
author_facet | Pradhan, Aishwarya Umesh Uwishema, Olivier Onyeaka, Helen Adanur, Irem Dost, Burhan |
author_sort | Pradhan, Aishwarya Umesh |
collection | PubMed |
description | AIM: This article aims to study the benefits and disadvantages of stem cell therapy, especially for patients who have dementia. METHODS: The databases PubMed, Google Scholar, and the National Library of Medicine were searched for literature. All papers on Alzheimer's disease, Lewy body dementia, Parkinson's disease, stem cell therapy, and its effect on dementia treatment were considered. RESULTS: Stem cell treatment has demonstrated promising outcomes in animal studies by positively modifying the degenerative alterations in dementia. However, it is not without drawbacks, such as ethical concerns while using embryonic stem cells and the danger of developing cancer if the cells undergo uncontrolled differentiation. CONCLUSION: Although stem cell therapy has its risks, it has the potential to be a viable therapeutic option for patients with dementia if developed appropriately. Hence, more research and clinical trials are needed to establish its efficacy in this context. |
format | Online Article Text |
id | pubmed-9480940 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-94809402022-09-28 A review of stem cell therapy: An emerging treatment for dementia in Alzheimer's and Parkinson's disease Pradhan, Aishwarya Umesh Uwishema, Olivier Onyeaka, Helen Adanur, Irem Dost, Burhan Brain Behav Reviews AIM: This article aims to study the benefits and disadvantages of stem cell therapy, especially for patients who have dementia. METHODS: The databases PubMed, Google Scholar, and the National Library of Medicine were searched for literature. All papers on Alzheimer's disease, Lewy body dementia, Parkinson's disease, stem cell therapy, and its effect on dementia treatment were considered. RESULTS: Stem cell treatment has demonstrated promising outcomes in animal studies by positively modifying the degenerative alterations in dementia. However, it is not without drawbacks, such as ethical concerns while using embryonic stem cells and the danger of developing cancer if the cells undergo uncontrolled differentiation. CONCLUSION: Although stem cell therapy has its risks, it has the potential to be a viable therapeutic option for patients with dementia if developed appropriately. Hence, more research and clinical trials are needed to establish its efficacy in this context. John Wiley and Sons Inc. 2022-08-15 /pmc/articles/PMC9480940/ /pubmed/35971625 http://dx.doi.org/10.1002/brb3.2740 Text en © 2022 The Authors. Brain and Behavior published by Wiley Periodicals LLC. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Reviews Pradhan, Aishwarya Umesh Uwishema, Olivier Onyeaka, Helen Adanur, Irem Dost, Burhan A review of stem cell therapy: An emerging treatment for dementia in Alzheimer's and Parkinson's disease |
title | A review of stem cell therapy: An emerging treatment for dementia in Alzheimer's and Parkinson's disease |
title_full | A review of stem cell therapy: An emerging treatment for dementia in Alzheimer's and Parkinson's disease |
title_fullStr | A review of stem cell therapy: An emerging treatment for dementia in Alzheimer's and Parkinson's disease |
title_full_unstemmed | A review of stem cell therapy: An emerging treatment for dementia in Alzheimer's and Parkinson's disease |
title_short | A review of stem cell therapy: An emerging treatment for dementia in Alzheimer's and Parkinson's disease |
title_sort | review of stem cell therapy: an emerging treatment for dementia in alzheimer's and parkinson's disease |
topic | Reviews |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9480940/ https://www.ncbi.nlm.nih.gov/pubmed/35971625 http://dx.doi.org/10.1002/brb3.2740 |
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