Engineered peptide PLG0206 overcomes limitations of a challenging antimicrobial drug class

The absence of novel antibiotics for drug-resistant and biofilm-associated infections is a global public health crisis. Antimicrobial peptides explored to address this need have encountered significant development challenges associated with size, toxicity, safety profile, and pharmacokinetics. We de...

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Detalles Bibliográficos
Autores principales: Huang, David B., Brothers, Kimberly M., Mandell, Jonathan B., Taguchi, Masashi, Alexander, Peter G., Parker, Dana M., Shinabarger, Dean, Pillar, Chris, Morrissey, Ian, Hawser, Stephen, Ghahramani, Parviz, Dobbins, Despina, Pachuda, Nicholas, Montelaro, Ronald, Steckbeck, Jonathan D., Urish, Kenneth L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9481017/
https://www.ncbi.nlm.nih.gov/pubmed/36112657
http://dx.doi.org/10.1371/journal.pone.0274815

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