Rapamycin treatment during development extends life span and health span of male mice and Daphnia magna

Development is tightly connected to aging, but whether pharmacologically targeting development can extend life remains unknown. Here, we subjected genetically diverse UMHET3 mice to rapamycin for the first 45 days of life. The mice grew slower and remained smaller than controls for their entire live...

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Detalles Bibliográficos
Autores principales: Shindyapina, Anastasia V., Cho, Yongmin, Kaya, Alaattin, Tyshkovskiy, Alexander, Castro, José P., Deik, Amy, Gordevicius, Juozas, Poganik, Jesse R., Clish, Clary B., Horvath, Steve, Peshkin, Leonid, Gladyshev, Vadim N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9481125/
https://www.ncbi.nlm.nih.gov/pubmed/36112674
http://dx.doi.org/10.1126/sciadv.abo5482

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