Cargando…

Oral zero-valent-molybdenum nanodots for inflammatory bowel disease therapy

Inflammatory bowel disease (IBD) affects millions of people each year. The overproduction of reactive oxygen species (ROS) plays a critical role in the progress of IBD and will be a potential therapeutic target. Here, we synthesize a kind of oral zero-valent-molybdenum nanodots (ZVMNs) for the treat...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Chen, Wang, Han, Yang, Xinhui, Fu, Zi, Ji, Xiuru, Shi, Yifan, Zhong, Jie, Hu, Weiguo, Ye, Youqiong, Wang, Zhengting, Ni, Dalong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for the Advancement of Science 2022
Materias:	Biomedicine and Life Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9481133/ https://www.ncbi.nlm.nih.gov/pubmed/36112678 http://dx.doi.org/10.1126/sciadv.abp9882

Ejemplares similares

Transformation of arginine into zero-dimensional nanomaterial endows the material with antibacterial and osteoinductive activity
por: Li, Jiaying, et al.
Publicado: (2023)

Urchin-like ceria nanoparticles for enhanced gene therapy of osteoarthritis
por: Chen, Haoyi, et al.
Publicado: (2023)

Mucoadhesive probiotic backpacks with ROS nanoscavengers enhance the bacteriotherapy for inflammatory bowel diseases
por: Liu, Jun, et al.
Publicado: (2022)

A nanoparticulate dual scavenger for targeted therapy of inflammatory bowel disease
por: Shi, Chengxin, et al.
Publicado: (2022)

ZBP1-MLKL necroptotic signaling potentiates radiation-induced antitumor immunity via intratumoral STING pathway activation
por: Yang, Yuanqin, et al.
Publicado: (2021)

Orally deliverable strategy based on microalgal biomass for intestinal disease treatment
por: Zhong, Danni, et al.
Publicado: (2021)

Interface confined hydrogen evolution reaction in zero valent metal nanoparticles-intercalated molybdenum disulfide
por: Chen, Zhongxin, et al.
Publicado: (2017)

Biointerface mineralization generates ultraresistant gut microbes as oral biotherapeutics
por: Geng, Zhongmin, et al.
Publicado: (2023)

m(6)A mRNA modification maintains colonic epithelial cell homeostasis via NF-κB–mediated antiapoptotic pathway
por: Zhang, Ting, et al.
Publicado: (2022)

Oral polyphenol-armored nanomedicine for targeted modulation of gut microbiota–brain interactions in colitis
por: He, Huan, et al.
Publicado: (2023)

A bispecific glycopeptide spatiotemporally regulates tumor microenvironment for inhibiting bladder cancer recurrence
por: An, Hong-Wei, et al.
Publicado: (2023)

Versatility of bacterial outer membrane vesicles in regulating intestinal homeostasis
por: Wang, Xinyue, et al.
Publicado: (2023)

Structural basis of plp2-mediated cytoskeletal protein folding by TRiC/CCT
por: Han, Wenyu, et al.
Publicado: (2023)

Dynamic omnidirectional adhesive microneedle system for oral macromolecular drug delivery
por: Chen, Wei, et al.
Publicado: (2022)

Bacterioboat—A novel tool to increase the half-life period of the orally administered drug
por: Kaur, Parmandeep, et al.
Publicado: (2022)

The role of ipRGCs in ocular growth and myopia development
por: Liu, Ai-Lin, et al.
Publicado: (2022)

Efficient oral insulin delivery enabled by transferrin-coated acid-resistant metal-organic framework nanoparticles
por: Zou, Jun-Jie, et al.
Publicado: (2022)

Orally efficacious lead of the AVG inhibitor series targeting a dynamic interface in the respiratory syncytial virus polymerase
por: Sourimant, Julien, et al.
Publicado: (2022)

Base editor enables rational genome-scale functional screening for enhanced industrial phenotypes in Corynebacterium glutamicum
por: Liu, Ye, et al.
Publicado: (2022)

Imaging of Escherichia coli K5 and glycosaminoglycan precursors via targeted metabolic labeling of capsular polysaccharides in bacteria
por: Wang, Yu-Jia, et al.
Publicado: (2023)

Tumor-associated nonmyelinating Schwann cell–expressed PVT1 promotes pancreatic cancer kynurenine pathway and tumor immune exclusion
por: Sun, Chengcao, et al.
Publicado: (2023)

Structure of a fungal 1,3-β-glucan synthase
por: Zhao, Chao-Ran, et al.
Publicado: (2023)

Dodecamer assembly of a metazoan AAA(+) chaperone couples substrate extraction to refolding
por: Gupta, Arpit, et al.
Publicado: (2023)

A transcriptomics-guided drug target discovery strategy identifies receptor ligands for lung regeneration
por: Wu, Xinhui, et al.
Publicado: (2022)

Single-cell and spatial transcriptome analysis reveals the cellular heterogeneity of liver metastatic colorectal cancer
por: Wang, Fei, et al.
Publicado: (2023)

Evolutionary epigenomic analyses in mammalian early embryos reveal species-specific innovations and conserved principles of imprinting
por: Lu, Xukun, et al.
Publicado: (2021)

TEAD4 is a master regulator of high-risk nasopharyngeal carcinoma
por: Wang, Ya-Qin, et al.
Publicado: (2023)

Ventromedial hypothalamic OGT drives adipose tissue lipolysis and curbs obesity
por: Wang, Qi, et al.
Publicado: (2022)

SMAD4, activated by the TCR-triggered MEK/ERK signaling pathway, critically regulates CD8(+) T cell cytotoxic function
por: Liu, Xinwei, et al.
Publicado: (2022)

Activation mechanism of a short argonaute-TIR prokaryotic immune system
por: Ni, Dongchun, et al.
Publicado: (2023)

Quantitative cross-species translators of cardiac myocyte electrophysiology: Model training, experimental validation, and applications
por: Morotti, Stefano, et al.
Publicado: (2021)

Natural flavonoids disrupt bacterial iron homeostasis to potentiate colistin efficacy
por: Zhong, Zi-xing, et al.
Publicado: (2023)

Nanoengineered on-demand drug delivery system improves efficacy of pharmacotherapy for epilepsy
por: Wu, Di, et al.
Publicado: (2022)

Augmenting L3MBTL2-induced condensates suppresses tumor growth in osteosarcoma
por: Zhong, Li, et al.
Publicado: (2023)

Interrogating glioma-M2 macrophage interactions identifies Gal-9/Tim-3 as a viable target against PTEN-null glioblastoma
por: Ni, Xiangrong, et al.
Publicado: (2022)

Co-condensation with photoexcited cryptochromes facilitates MAC3A to positively control hypocotyl growth in Arabidopsis
por: Jiang, Bochen, et al.
Publicado: (2023)

Iron oxide nanoparticles augment the intercellular mitochondrial transfer–mediated therapy
por: Huang, Ting, et al.
Publicado: (2021)

A BMP-2–triggered in vivo osteo-organoid for cell therapy
por: Dai, Kai, et al.
Publicado: (2023)

Metabolite asymmetric dimethylarginine (ADMA) functions as a destabilization enhancer of SOX9 mediated by DDAH1 in osteoarthritis
por: Wu, Yizheng, et al.
Publicado: (2023)

Inhibiting sorting nexin 10 promotes mucosal healing through SREBP2-mediated stemness restoration of intestinal stem cells
por: Bao, Weilian, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_6krdbgk1nqrko77liotb1itnie