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A Malignant Connection: Bronchoesophageal-Pleural Fistula in an Elderly Farmer

Bronchoesophageal-pleural fistula (BEPF) is a very rare entity that can present as a late manifestation of oesophageal malignancy. Here, we describe the case of an elderly farmer with no past medical history of note who presented with acute respiratory failure associated with a five-month history of...

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Autores principales: Gaine, Sam, Danish, Hammad, Binalialsharabi, Wail, Fennessy, Sean, Morcos, Ashraf, Rogan, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9481227/
https://www.ncbi.nlm.nih.gov/pubmed/36134059
http://dx.doi.org/10.7759/cureus.27966
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author Gaine, Sam
Danish, Hammad
Binalialsharabi, Wail
Fennessy, Sean
Morcos, Ashraf
Rogan, Mark
author_facet Gaine, Sam
Danish, Hammad
Binalialsharabi, Wail
Fennessy, Sean
Morcos, Ashraf
Rogan, Mark
author_sort Gaine, Sam
collection PubMed
description Bronchoesophageal-pleural fistula (BEPF) is a very rare entity that can present as a late manifestation of oesophageal malignancy. Here, we describe the case of an elderly farmer with no past medical history of note who presented with acute respiratory failure associated with a five-month history of dysphagia and weight loss. Computerised tomography of the thorax showed a connection between the oesophagus, bronchus and pleural space: a bronchoesophageal-pleural fistula. Ultrasound-guided thoracentesis was followed by chest drain insertion into an empyema containing food debris. Histopathological analysis of endoscopic biopsies confirmed an eroding squamous cell carcinoma (SCC) of the oesophagus. An oesophageal stent was inserted to seal off the fistula and broad-spectrum antibiotics were maximised. Ultimately, after four weeks in hospital, palliative therapy was initiated. BEPF remains a very rare and devastating complication of oesophageal malignancy. Endoscopic stenting may provide symptomatic relief.
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spelling pubmed-94812272022-09-20 A Malignant Connection: Bronchoesophageal-Pleural Fistula in an Elderly Farmer Gaine, Sam Danish, Hammad Binalialsharabi, Wail Fennessy, Sean Morcos, Ashraf Rogan, Mark Cureus Gastroenterology Bronchoesophageal-pleural fistula (BEPF) is a very rare entity that can present as a late manifestation of oesophageal malignancy. Here, we describe the case of an elderly farmer with no past medical history of note who presented with acute respiratory failure associated with a five-month history of dysphagia and weight loss. Computerised tomography of the thorax showed a connection between the oesophagus, bronchus and pleural space: a bronchoesophageal-pleural fistula. Ultrasound-guided thoracentesis was followed by chest drain insertion into an empyema containing food debris. Histopathological analysis of endoscopic biopsies confirmed an eroding squamous cell carcinoma (SCC) of the oesophagus. An oesophageal stent was inserted to seal off the fistula and broad-spectrum antibiotics were maximised. Ultimately, after four weeks in hospital, palliative therapy was initiated. BEPF remains a very rare and devastating complication of oesophageal malignancy. Endoscopic stenting may provide symptomatic relief. Cureus 2022-08-13 /pmc/articles/PMC9481227/ /pubmed/36134059 http://dx.doi.org/10.7759/cureus.27966 Text en Copyright © 2022, Gaine et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Gastroenterology
Gaine, Sam
Danish, Hammad
Binalialsharabi, Wail
Fennessy, Sean
Morcos, Ashraf
Rogan, Mark
A Malignant Connection: Bronchoesophageal-Pleural Fistula in an Elderly Farmer
title A Malignant Connection: Bronchoesophageal-Pleural Fistula in an Elderly Farmer
title_full A Malignant Connection: Bronchoesophageal-Pleural Fistula in an Elderly Farmer
title_fullStr A Malignant Connection: Bronchoesophageal-Pleural Fistula in an Elderly Farmer
title_full_unstemmed A Malignant Connection: Bronchoesophageal-Pleural Fistula in an Elderly Farmer
title_short A Malignant Connection: Bronchoesophageal-Pleural Fistula in an Elderly Farmer
title_sort malignant connection: bronchoesophageal-pleural fistula in an elderly farmer
topic Gastroenterology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9481227/
https://www.ncbi.nlm.nih.gov/pubmed/36134059
http://dx.doi.org/10.7759/cureus.27966
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