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Unexpected favorable outcome to sintilimab monotherapy in a relapse pancreatic ductal adenocarcinoma patient with high tumor mutational burden: a case report
The reason that immune checkpoint inhibitors have not been widely applied to pancreatic cancer treatment is probably because of low immunogenicity or dense stromal fibrosis. Recently, only pembrolizumab was recommended for DNA mismatch repair deficiency or high microsatellite instability by National...
Autores principales: | Zhang, Fan, Li, Xiaomin, Liu, Haisheng, Liu, Rongfeng, Zhou, Zhiguo, Zhang, Yi, Chen, Jingli, Tian, Ye, Pan, Chaohu, Meng, Qingju, Liu, Yibing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9481288/ https://www.ncbi.nlm.nih.gov/pubmed/35946538 http://dx.doi.org/10.1097/CAD.0000000000001334 |
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