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Pancancer Analysis of Revealed TDO2 as a Biomarker of Prognosis and Immunotherapy
BACKGROUND: Tryptophan 2,3-dioxygenase (TDO) encoded by TDO2, a rate-limiting enzyme in the kynurenine pathway, catabolizes tryptophan to kynurenine, evades immune surveillance, and promotes tumor growth. Although accumulating evidence suggests a crucial role of TDO2 during tumor formation and devel...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Hindawi
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9481368/ https://www.ncbi.nlm.nih.gov/pubmed/36118672 http://dx.doi.org/10.1155/2022/5447017 |