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A proof of concept for targeting the PrP(C) - Amyloid β peptide interaction in basal prostate cancer and mesenchymal colon cancer

The cellular prion protein PrP(C) partners with caveolin-1 (CAV1) in neurodegenerative diseases but whether this interplay occurs in cancer has never been investigated. By leveraging patient and cell line datasets, we uncover a molecular link between PrP(C) and CAV1 across cancer. Using cell-based a...

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Detalles Bibliográficos
Autores principales:	Mouillet-Richard, Sophie, Martin-Lannerée, Séverine, Le Corre, Delphine, Hirsch, Théo Z., Ghazi, Alexandre, Sroussi, Marine, Pilati, Camilla, de Reyniès, Aurélien, Djouadi, Fatima, Vodovar, Nicolas, Launay, Jean-Marie, Laurent-Puig, Pierre
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Brief Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9481457/ https://www.ncbi.nlm.nih.gov/pubmed/35962130 http://dx.doi.org/10.1038/s41388-022-02430-7

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