Forming cytoplasmic stress granules PURα suppresses mRNA translation initiation of IGFBP3 to promote esophageal squamous cell carcinoma progression

Esophageal squamous cell carcinoma (ESCC) is one of the most fatal malignancies worldwide. Recently, our group identified purine-rich element binding protein alpha (PURα), a single-stranded DNA/RNA-binding protein, to be significantly associated with the progression of ESCC. Additional immunofluores...

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Detalles Bibliográficos
Autores principales: Tian, Lusong, Xie, Xiufeng, Das, Urmi, Chen, Yuling, Sun, Yulin, Liu, Fang, Lu, Haizhen, Nan, Peng, Zhu, Ying, Gu, Xinglu, Deng, Haiteng, Xie, Jiuyong, Zhao, Xiaohang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9481463/
https://www.ncbi.nlm.nih.gov/pubmed/35945453
http://dx.doi.org/10.1038/s41388-022-02426-3

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