Medical therapy for patients with recent-onset heart failure with reduced ejection fraction during the COVID-19 pandemic: Insights from the Veteran's affairs healthcare system

This study aims to evaluate trends in guideline-directed medical therapy (GDMT) for patients with recent-onset heart failure with reduced ejection fraction (HFrEF) following the onset of the COVID-19 pandemic using an interrupted time series analysis in the Veteran's Affairs Healthcare System....

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Detalles Bibliográficos
Autores principales: Sandhu, Alexander T., Zheng, Jimmy, Tisdale, Rebecca L., Kohsaka, Shun, Turakhia, Mintu P., Heidenreich, Paul A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9481472/
https://www.ncbi.nlm.nih.gov/pubmed/36156887
http://dx.doi.org/10.1016/j.ahjo.2022.100210
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author Sandhu, Alexander T.
Zheng, Jimmy
Tisdale, Rebecca L.
Kohsaka, Shun
Turakhia, Mintu P.
Heidenreich, Paul A.
author_facet Sandhu, Alexander T.
Zheng, Jimmy
Tisdale, Rebecca L.
Kohsaka, Shun
Turakhia, Mintu P.
Heidenreich, Paul A.
author_sort Sandhu, Alexander T.
collection PubMed
description This study aims to evaluate trends in guideline-directed medical therapy (GDMT) for patients with recent-onset heart failure with reduced ejection fraction (HFrEF) following the onset of the COVID-19 pandemic using an interrupted time series analysis in the Veteran's Affairs Healthcare System. Among 71,428 patients with recent-onset HFrEF between 1/1/2018 and 2/28/2021, we found the pandemic was not associated with differences in treatment rates for beta-blockers, renin-angiotensin-aldosterone system inhibitors, or mineralocorticoid receptor antagonists; there was a 2.6 % absolute decrease (95 % CI: 0.5 %–4.7 %) in ARNI rates in April 2020; which decreased over the pandemic. Despite the changes to healthcare delivery, the COVID-19 pandemic was associated with minimal changes in GDMT rates among patients with recent-onset HFrEF.
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spelling pubmed-94814722022-09-19 Medical therapy for patients with recent-onset heart failure with reduced ejection fraction during the COVID-19 pandemic: Insights from the Veteran's affairs healthcare system Sandhu, Alexander T. Zheng, Jimmy Tisdale, Rebecca L. Kohsaka, Shun Turakhia, Mintu P. Heidenreich, Paul A. Am Heart J Plus Short Communication This study aims to evaluate trends in guideline-directed medical therapy (GDMT) for patients with recent-onset heart failure with reduced ejection fraction (HFrEF) following the onset of the COVID-19 pandemic using an interrupted time series analysis in the Veteran's Affairs Healthcare System. Among 71,428 patients with recent-onset HFrEF between 1/1/2018 and 2/28/2021, we found the pandemic was not associated with differences in treatment rates for beta-blockers, renin-angiotensin-aldosterone system inhibitors, or mineralocorticoid receptor antagonists; there was a 2.6 % absolute decrease (95 % CI: 0.5 %–4.7 %) in ARNI rates in April 2020; which decreased over the pandemic. Despite the changes to healthcare delivery, the COVID-19 pandemic was associated with minimal changes in GDMT rates among patients with recent-onset HFrEF. Elsevier 2022-10 2022-09-17 /pmc/articles/PMC9481472/ /pubmed/36156887 http://dx.doi.org/10.1016/j.ahjo.2022.100210 Text en Published by Elsevier Inc. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Short Communication
Sandhu, Alexander T.
Zheng, Jimmy
Tisdale, Rebecca L.
Kohsaka, Shun
Turakhia, Mintu P.
Heidenreich, Paul A.
Medical therapy for patients with recent-onset heart failure with reduced ejection fraction during the COVID-19 pandemic: Insights from the Veteran's affairs healthcare system
title Medical therapy for patients with recent-onset heart failure with reduced ejection fraction during the COVID-19 pandemic: Insights from the Veteran's affairs healthcare system
title_full Medical therapy for patients with recent-onset heart failure with reduced ejection fraction during the COVID-19 pandemic: Insights from the Veteran's affairs healthcare system
title_fullStr Medical therapy for patients with recent-onset heart failure with reduced ejection fraction during the COVID-19 pandemic: Insights from the Veteran's affairs healthcare system
title_full_unstemmed Medical therapy for patients with recent-onset heart failure with reduced ejection fraction during the COVID-19 pandemic: Insights from the Veteran's affairs healthcare system
title_short Medical therapy for patients with recent-onset heart failure with reduced ejection fraction during the COVID-19 pandemic: Insights from the Veteran's affairs healthcare system
title_sort medical therapy for patients with recent-onset heart failure with reduced ejection fraction during the covid-19 pandemic: insights from the veteran's affairs healthcare system
topic Short Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9481472/
https://www.ncbi.nlm.nih.gov/pubmed/36156887
http://dx.doi.org/10.1016/j.ahjo.2022.100210
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