Reevaluation of antibody-dependent enhancement of infection in anti-SARS-CoV-2 therapeutic antibodies and mRNA-vaccine antisera using FcR- and ACE2-positive cells

Many therapeutic antibodies (Abs) and mRNA vaccines, both targeting SARS-CoV-2 spike protein (S-protein), have been developed and approved in order to combat the ongoing COVID-19 pandemic. In consideration of these developments, a common concern has been the potential for Ab-dependent enhancement (A...

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Detalles Bibliográficos
Autores principales: Shimizu, Jun, Sasaki, Tadahiro, Koketsu, Ritsuko, Morita, Ryo, Yoshimura, Yuka, Murakami, Ami, Saito, Yua, Kusunoki, Toshie, Samune, Yoshihiro, Nakayama, Emi E., Miyazaki, Kazuo, Shioda, Tatsuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9481526/
https://www.ncbi.nlm.nih.gov/pubmed/36114224
http://dx.doi.org/10.1038/s41598-022-19993-w

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