Cargando…

Bos taurus (A-2) urine assisted bioactive cobalt oxide anchored ZnO: a novel nanoscale approach

In this study, a novel synthetic method for cobalt oxide (Co(3)O(4)) nanoparticles using Bos taurus (A-2) urine as a reducing agent was developed. In addition to this ZnO nanorods were produced hydrothermally and a nanocomposite is formed through a solid-state reaction. The synthesized materials wer...

Descripción completa

Detalles Bibliográficos
Autores principales: Karvekar, Omkar S., Vadanagekar, Apurva S., Sarvalkar, Prashant D., Suryawanshi, Suresh S., Jadhav, Sarita M., Singhan, Richa D., Jadhav, Jyoti P., Sharma, Kiran Kumar K., Prasad, Neeraj R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9481578/
https://www.ncbi.nlm.nih.gov/pubmed/36114411
http://dx.doi.org/10.1038/s41598-022-19900-3
_version_ 1784791300592107520
author Karvekar, Omkar S.
Vadanagekar, Apurva S.
Sarvalkar, Prashant D.
Suryawanshi, Suresh S.
Jadhav, Sarita M.
Singhan, Richa D.
Jadhav, Jyoti P.
Sharma, Kiran Kumar K.
Prasad, Neeraj R.
author_facet Karvekar, Omkar S.
Vadanagekar, Apurva S.
Sarvalkar, Prashant D.
Suryawanshi, Suresh S.
Jadhav, Sarita M.
Singhan, Richa D.
Jadhav, Jyoti P.
Sharma, Kiran Kumar K.
Prasad, Neeraj R.
author_sort Karvekar, Omkar S.
collection PubMed
description In this study, a novel synthetic method for cobalt oxide (Co(3)O(4)) nanoparticles using Bos taurus (A-2) urine as a reducing agent was developed. In addition to this ZnO nanorods were produced hydrothermally and a nanocomposite is formed through a solid-state reaction. The synthesized materials were characterized through modern characterization techniques such as XRD, FE-SEM with EDS, DLS, zeta potential, FT-IR, Raman spectroscopic analysis, and TGA with DSC. The free radical destructive activity was determined using two different methods viz. ABTS and DPPH. The potential for BSA denaturation in vitro, which is measured in comparison to heat-induced denaturation of egg albumin and results in anti-inflammatory effects of nanomaterial was studied. All synthesized nanomaterials have excellent antibacterial properties, particularly against Salmonella typhi and Staphylococcus aureus. The composite exhibits excellent antioxidant and anti-inflammatory activities in comparison to pure nanomaterials. This reveals that these nanomaterials are advantageous in medicine and drug administration.
format Online
Article
Text
id pubmed-9481578
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Nature Publishing Group UK
record_format MEDLINE/PubMed
spelling pubmed-94815782022-09-18 Bos taurus (A-2) urine assisted bioactive cobalt oxide anchored ZnO: a novel nanoscale approach Karvekar, Omkar S. Vadanagekar, Apurva S. Sarvalkar, Prashant D. Suryawanshi, Suresh S. Jadhav, Sarita M. Singhan, Richa D. Jadhav, Jyoti P. Sharma, Kiran Kumar K. Prasad, Neeraj R. Sci Rep Article In this study, a novel synthetic method for cobalt oxide (Co(3)O(4)) nanoparticles using Bos taurus (A-2) urine as a reducing agent was developed. In addition to this ZnO nanorods were produced hydrothermally and a nanocomposite is formed through a solid-state reaction. The synthesized materials were characterized through modern characterization techniques such as XRD, FE-SEM with EDS, DLS, zeta potential, FT-IR, Raman spectroscopic analysis, and TGA with DSC. The free radical destructive activity was determined using two different methods viz. ABTS and DPPH. The potential for BSA denaturation in vitro, which is measured in comparison to heat-induced denaturation of egg albumin and results in anti-inflammatory effects of nanomaterial was studied. All synthesized nanomaterials have excellent antibacterial properties, particularly against Salmonella typhi and Staphylococcus aureus. The composite exhibits excellent antioxidant and anti-inflammatory activities in comparison to pure nanomaterials. This reveals that these nanomaterials are advantageous in medicine and drug administration. Nature Publishing Group UK 2022-09-16 /pmc/articles/PMC9481578/ /pubmed/36114411 http://dx.doi.org/10.1038/s41598-022-19900-3 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Karvekar, Omkar S.
Vadanagekar, Apurva S.
Sarvalkar, Prashant D.
Suryawanshi, Suresh S.
Jadhav, Sarita M.
Singhan, Richa D.
Jadhav, Jyoti P.
Sharma, Kiran Kumar K.
Prasad, Neeraj R.
Bos taurus (A-2) urine assisted bioactive cobalt oxide anchored ZnO: a novel nanoscale approach
title Bos taurus (A-2) urine assisted bioactive cobalt oxide anchored ZnO: a novel nanoscale approach
title_full Bos taurus (A-2) urine assisted bioactive cobalt oxide anchored ZnO: a novel nanoscale approach
title_fullStr Bos taurus (A-2) urine assisted bioactive cobalt oxide anchored ZnO: a novel nanoscale approach
title_full_unstemmed Bos taurus (A-2) urine assisted bioactive cobalt oxide anchored ZnO: a novel nanoscale approach
title_short Bos taurus (A-2) urine assisted bioactive cobalt oxide anchored ZnO: a novel nanoscale approach
title_sort bos taurus (a-2) urine assisted bioactive cobalt oxide anchored zno: a novel nanoscale approach
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9481578/
https://www.ncbi.nlm.nih.gov/pubmed/36114411
http://dx.doi.org/10.1038/s41598-022-19900-3
work_keys_str_mv AT karvekaromkars bostaurusa2urineassistedbioactivecobaltoxideanchoredznoanovelnanoscaleapproach
AT vadanagekarapurvas bostaurusa2urineassistedbioactivecobaltoxideanchoredznoanovelnanoscaleapproach
AT sarvalkarprashantd bostaurusa2urineassistedbioactivecobaltoxideanchoredznoanovelnanoscaleapproach
AT suryawanshisureshs bostaurusa2urineassistedbioactivecobaltoxideanchoredznoanovelnanoscaleapproach
AT jadhavsaritam bostaurusa2urineassistedbioactivecobaltoxideanchoredznoanovelnanoscaleapproach
AT singhanrichad bostaurusa2urineassistedbioactivecobaltoxideanchoredznoanovelnanoscaleapproach
AT jadhavjyotip bostaurusa2urineassistedbioactivecobaltoxideanchoredznoanovelnanoscaleapproach
AT sharmakirankumark bostaurusa2urineassistedbioactivecobaltoxideanchoredznoanovelnanoscaleapproach
AT prasadneerajr bostaurusa2urineassistedbioactivecobaltoxideanchoredznoanovelnanoscaleapproach