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FVC as an adaptive and accurate method for filtering variants from popular NGS analysis pipelines
The quality control of variants from whole-genome sequencing data is vital in clinical diagnosis and human genetics research. However, current filtering methods (Frequency, Hard-Filter, VQSR, GARFIELD, and VEF) were developed to be utilized on particular variant callers and have certain limitations....
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9481582/ https://www.ncbi.nlm.nih.gov/pubmed/36114280 http://dx.doi.org/10.1038/s42003-022-03397-7 |