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Conformational transitions of the Spindly adaptor underlie its interaction with Dynein and Dynactin

Cytoplasmic Dynein 1, or Dynein, is a microtubule minus end–directed motor. Dynein motility requires Dynactin and a family of activating adaptors that stabilize the Dynein–Dynactin complex and promote regulated interactions with cargo in space and time. How activating adaptors limit Dynein activatio...

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Detalles Bibliográficos
Autores principales:	d’Amico, Ennio A., Ud Din Ahmad, Misbha, Cmentowski, Verena, Girbig, Mathias, Müller, Franziska, Wohlgemuth, Sabine, Brockmeyer, Andreas, Maffini, Stefano, Janning, Petra, Vetter, Ingrid R., Carter, Andrew P., Perrakis, Anastassis, Musacchio, Andrea
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Rockefeller University Press 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9481740/ https://www.ncbi.nlm.nih.gov/pubmed/36107127 http://dx.doi.org/10.1083/jcb.202206131

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