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Anti-TGF-β1 aptamer enhances therapeutic effect of tyrosine kinase inhibitor, gefitinib, on non-small cell lung cancer in xenograft model

Transforming growth factor β (TGF-β) is a multifunctional cytokine that plays crucial pathophysiological roles in various diseases, such as cancer and fibrosis. However, the disease modulation by targeting TGF-β1 isoform remains to be established, regardless of several studies employed with limited...

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Detalles Bibliográficos
Autores principales: Takahashi, Masaki, Hashimoto, Yoshifumi, Nakamura, Yoshikazu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9481871/
https://www.ncbi.nlm.nih.gov/pubmed/36189081
http://dx.doi.org/10.1016/j.omtn.2022.06.001