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P450 oxidoreductase regulates barrier maturation by mediating retinoic acid metabolism in a model of the human BBB

The blood-brain barrier (BBB) selectively regulates the entry of molecules into the central nervous system (CNS). A crosstalk between brain microvascular endothelial cells (BMECs) and resident CNS cells promotes the acquisition of functional tight junctions (TJs). Retinoic acid (RA), a key signaling...

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Detalles Bibliográficos
Autores principales:	Zlotnik, Dor, Rabinski, Tatiana, Halfon, Aviv, Anzi, Shira, Plaschkes, Inbar, Benyamini, Hadar, Nevo, Yuval, Gershoni, Orly Yahalom, Rosental, Benyamin, Hershkovitz, Eli, Ben-Zvi, Ayal, Vatine, Gad D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9481905/ https://www.ncbi.nlm.nih.gov/pubmed/35961311 http://dx.doi.org/10.1016/j.stemcr.2022.07.010

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