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Development of a platform to investigate long-term potentiation in human iPSC-derived neuronal networks

Impairment of long-term potentiation (LTP) is a common feature of many pre-clinical models of neurological disorders; however, studies in humans are limited by the inaccessibility of the brain. Human induced pluripotent stem cells (hiPSCs) provide a unique opportunity to study LTP in disease-specifi...

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Detalles Bibliográficos
Autores principales: Pré, Deborah, Wooten, Alexander T., Biesmans, Steven, Hinckley, Sandy, Zhou, Haowen, Sherman, Sean P., Kakad, Priyanka, Gearhart, Jeffrey, Bang, Anne G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9481914/
https://www.ncbi.nlm.nih.gov/pubmed/35985330
http://dx.doi.org/10.1016/j.stemcr.2022.07.012