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Omicron variant: Current insights and future directions
The global COVID-19 outbreak has returned with the identification of the SARS-CoV-2 Omicron variant (B.1.1.529) after appearing to be persistently spreading for the more than past two years. In comparison to prior SARS-CoV-2 variants, this new variant revealed a significant amount of mutation. This...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier GmbH.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9482093/ https://www.ncbi.nlm.nih.gov/pubmed/36152612 http://dx.doi.org/10.1016/j.micres.2022.127204 |
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author | Rana, Rashmi Kant, Ravi Huirem, Rohit Singh Bohra, Deepika Ganguly, Nirmal Kumar |
author_facet | Rana, Rashmi Kant, Ravi Huirem, Rohit Singh Bohra, Deepika Ganguly, Nirmal Kumar |
author_sort | Rana, Rashmi |
collection | PubMed |
description | The global COVID-19 outbreak has returned with the identification of the SARS-CoV-2 Omicron variant (B.1.1.529) after appearing to be persistently spreading for the more than past two years. In comparison to prior SARS-CoV-2 variants, this new variant revealed a significant amount of mutation. This novel variety may have a greater rate of transmissibility which might impede the effectiveness of current diagnostic equipment as well as vaccination efficacy and also impede immunotherapies (Antibody / monoclonal antibody based). WHO designated B.1.1.529 as a variant of concern on November 26, 2021, identified as Omicron. The Omicron variant transmission method and severity, on the other hand, are well defined. The global spread of Omicron, which has now seized many nations, has resulted in numerous speculations regarding its origin and degree of infectivity. The following sections will go over its potential for transmission, omicron structure, and impact on COVID-19 vaccines, how it is different from delta variant and diagnostics. |
format | Online Article Text |
id | pubmed-9482093 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Elsevier GmbH. |
record_format | MEDLINE/PubMed |
spelling | pubmed-94820932022-09-19 Omicron variant: Current insights and future directions Rana, Rashmi Kant, Ravi Huirem, Rohit Singh Bohra, Deepika Ganguly, Nirmal Kumar Microbiol Res Article The global COVID-19 outbreak has returned with the identification of the SARS-CoV-2 Omicron variant (B.1.1.529) after appearing to be persistently spreading for the more than past two years. In comparison to prior SARS-CoV-2 variants, this new variant revealed a significant amount of mutation. This novel variety may have a greater rate of transmissibility which might impede the effectiveness of current diagnostic equipment as well as vaccination efficacy and also impede immunotherapies (Antibody / monoclonal antibody based). WHO designated B.1.1.529 as a variant of concern on November 26, 2021, identified as Omicron. The Omicron variant transmission method and severity, on the other hand, are well defined. The global spread of Omicron, which has now seized many nations, has resulted in numerous speculations regarding its origin and degree of infectivity. The following sections will go over its potential for transmission, omicron structure, and impact on COVID-19 vaccines, how it is different from delta variant and diagnostics. Elsevier GmbH. 2022-12 2022-09-17 /pmc/articles/PMC9482093/ /pubmed/36152612 http://dx.doi.org/10.1016/j.micres.2022.127204 Text en © 2022 Elsevier GmbH. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. |
spellingShingle | Article Rana, Rashmi Kant, Ravi Huirem, Rohit Singh Bohra, Deepika Ganguly, Nirmal Kumar Omicron variant: Current insights and future directions |
title | Omicron variant: Current insights and future directions |
title_full | Omicron variant: Current insights and future directions |
title_fullStr | Omicron variant: Current insights and future directions |
title_full_unstemmed | Omicron variant: Current insights and future directions |
title_short | Omicron variant: Current insights and future directions |
title_sort | omicron variant: current insights and future directions |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9482093/ https://www.ncbi.nlm.nih.gov/pubmed/36152612 http://dx.doi.org/10.1016/j.micres.2022.127204 |
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