Deletion of mdig enhances H3K36me3 and metastatic potential of the triple negative breast cancer cells

In this report, we provide evidence showing diminished expression of the mineral dust-induced gene (mdig), a previously identified oncogenic gene, in human triple negative breast cancer (TNBC). Using a mouse model of orthotopic xenograft of the TNBC MDA-MB-231 cells, we demonstrate that mdig promote...

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Detalles Bibliográficos
Autores principales: Thakur, Chitra, Qiu, Yiran, Zhang, Qian, Carruthers, Nicholas J., Yu, Miaomiao, Bi, Zhuoyue, Fu, Yao, Wadgaonkar, Priya, Almutairy, Bandar, Seno, Akimasa, Stemmer, Paul M., Chen, Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9482110/
https://www.ncbi.nlm.nih.gov/pubmed/36124233
http://dx.doi.org/10.1016/j.isci.2022.105057

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