Inhibition of APOC1 promotes the transformation of M2 into M1 macrophages via the ferroptosis pathway and enhances anti-PD1 immunotherapy in hepatocellular carcinoma based on single-cell RNA sequencing

Single-cell RNA-sequencing (scRNA-seq) presents better insights into cell behavior in the context of a complex tumor microenvironment by profiling single-cell populations. However, the mechanisms underlying treatment failure in hepatocellular carcinoma (HCC) are poorly understood. In this study, we...

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Detalles Bibliográficos
Autores principales: Hao, Xiaopei, Zheng, Zhiying, Liu, Hanyuan, Zhang, Yao, Kang, Junwei, Kong, Xiangyi, Rong, Dawei, Sun, Guangshun, Sun, Guoqiang, Liu, Li, Yu, Haibo, Tang, Weiwei, Wang, Xuehao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9482117/
https://www.ncbi.nlm.nih.gov/pubmed/36108528
http://dx.doi.org/10.1016/j.redox.2022.102463

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