Cargando…

High physical activity and ovarian reserve: a prospective study of normo-ovulatory professional athletes

BACKGROUND: This study investigated whether high physical activity affects ovarian reserve in normo-ovulatory, reproductive-age women. METHODS: This prospective, observational study compared 31 professional female athletes, with 31 women who did not engage in physical activity. It was conducted 2017...

Descripción completa

Detalles Bibliográficos
Autores principales: Miller, Netanella, Pasternak, Yael, Herzberger, Einat Haikin, Gluska, Hadar, Dorenstein, Chen, Rahav, Roni, Hemi, Rina, Zada, Nahid, Wiser, Amir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9482187/
https://www.ncbi.nlm.nih.gov/pubmed/36114550
http://dx.doi.org/10.1186/s13048-022-01040-x
_version_ 1784791397906251776
author Miller, Netanella
Pasternak, Yael
Herzberger, Einat Haikin
Gluska, Hadar
Dorenstein, Chen
Rahav, Roni
Hemi, Rina
Zada, Nahid
Wiser, Amir
author_facet Miller, Netanella
Pasternak, Yael
Herzberger, Einat Haikin
Gluska, Hadar
Dorenstein, Chen
Rahav, Roni
Hemi, Rina
Zada, Nahid
Wiser, Amir
author_sort Miller, Netanella
collection PubMed
description BACKGROUND: This study investigated whether high physical activity affects ovarian reserve in normo-ovulatory, reproductive-age women. METHODS: This prospective, observational study compared 31 professional female athletes, with 31 women who did not engage in physical activity. It was conducted 2017–2020 in a tertiary medical center. Normo-ovulatory, professional athletes, ages 20–35 years were recruited from The Wingate Institute—the Israeli National Institute for Sport Excellence. They had high International Physical Activity Questionnaire (IPAQ) scores. Non-physically active women, matched by age and body mass index, were recruited from hospital staff. Women were evaluated for ovarian reserve markers on day 2–5 of the menstrual cycle, including follicular stimulating hormone, antral follicle count, anti-Mullerian hormone and Inhibin B. RESULTS: The average age of the high physical activity group was 29.9 ± 4.2 years and the nonactive group 31.6 ± 4.2 years (p = 0.062). Body mass index of both groups were similar (22.5 ± 5.0 vs. 21.4 ± 2.5, respectively; p = 0.1). No differences were observed with respect to follicle stimulating hormone (p = 0.12) and anti-Mullerian hormone (p = 0.16). A trend towards higher total antral follicle count in the high physical activity group vs. the non-active group (34.5 ± 12.9 vs. 28.1 ± 15.2, p = 0.08) and lower Inhibin B (68.1 ± 36.8 vs. 89.4 ± 46.1, p = 0.05). Menarche age correlated with anti-Mullerian hormone (r = 0.387, p = 0.003), as did total antral follicle count (r = 0.368, p = 0.004). IPAQ scores and basal follicle stimulating hormone levels were negatively correlated (r = − 0.292, p = 0.005). CONCLUSIONS: Athletic, normo-ovulatory women have ovarian reserves that are at least as good as those of the general population. As this is the first study examining this issue, it could cautiously reassure women engaged in high physical activity regarding ovarian reserve.
format Online
Article
Text
id pubmed-9482187
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher BioMed Central
record_format MEDLINE/PubMed
spelling pubmed-94821872022-09-18 High physical activity and ovarian reserve: a prospective study of normo-ovulatory professional athletes Miller, Netanella Pasternak, Yael Herzberger, Einat Haikin Gluska, Hadar Dorenstein, Chen Rahav, Roni Hemi, Rina Zada, Nahid Wiser, Amir J Ovarian Res Research BACKGROUND: This study investigated whether high physical activity affects ovarian reserve in normo-ovulatory, reproductive-age women. METHODS: This prospective, observational study compared 31 professional female athletes, with 31 women who did not engage in physical activity. It was conducted 2017–2020 in a tertiary medical center. Normo-ovulatory, professional athletes, ages 20–35 years were recruited from The Wingate Institute—the Israeli National Institute for Sport Excellence. They had high International Physical Activity Questionnaire (IPAQ) scores. Non-physically active women, matched by age and body mass index, were recruited from hospital staff. Women were evaluated for ovarian reserve markers on day 2–5 of the menstrual cycle, including follicular stimulating hormone, antral follicle count, anti-Mullerian hormone and Inhibin B. RESULTS: The average age of the high physical activity group was 29.9 ± 4.2 years and the nonactive group 31.6 ± 4.2 years (p = 0.062). Body mass index of both groups were similar (22.5 ± 5.0 vs. 21.4 ± 2.5, respectively; p = 0.1). No differences were observed with respect to follicle stimulating hormone (p = 0.12) and anti-Mullerian hormone (p = 0.16). A trend towards higher total antral follicle count in the high physical activity group vs. the non-active group (34.5 ± 12.9 vs. 28.1 ± 15.2, p = 0.08) and lower Inhibin B (68.1 ± 36.8 vs. 89.4 ± 46.1, p = 0.05). Menarche age correlated with anti-Mullerian hormone (r = 0.387, p = 0.003), as did total antral follicle count (r = 0.368, p = 0.004). IPAQ scores and basal follicle stimulating hormone levels were negatively correlated (r = − 0.292, p = 0.005). CONCLUSIONS: Athletic, normo-ovulatory women have ovarian reserves that are at least as good as those of the general population. As this is the first study examining this issue, it could cautiously reassure women engaged in high physical activity regarding ovarian reserve. BioMed Central 2022-09-16 /pmc/articles/PMC9482187/ /pubmed/36114550 http://dx.doi.org/10.1186/s13048-022-01040-x Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research
Miller, Netanella
Pasternak, Yael
Herzberger, Einat Haikin
Gluska, Hadar
Dorenstein, Chen
Rahav, Roni
Hemi, Rina
Zada, Nahid
Wiser, Amir
High physical activity and ovarian reserve: a prospective study of normo-ovulatory professional athletes
title High physical activity and ovarian reserve: a prospective study of normo-ovulatory professional athletes
title_full High physical activity and ovarian reserve: a prospective study of normo-ovulatory professional athletes
title_fullStr High physical activity and ovarian reserve: a prospective study of normo-ovulatory professional athletes
title_full_unstemmed High physical activity and ovarian reserve: a prospective study of normo-ovulatory professional athletes
title_short High physical activity and ovarian reserve: a prospective study of normo-ovulatory professional athletes
title_sort high physical activity and ovarian reserve: a prospective study of normo-ovulatory professional athletes
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9482187/
https://www.ncbi.nlm.nih.gov/pubmed/36114550
http://dx.doi.org/10.1186/s13048-022-01040-x
work_keys_str_mv AT millernetanella highphysicalactivityandovarianreserveaprospectivestudyofnormoovulatoryprofessionalathletes
AT pasternakyael highphysicalactivityandovarianreserveaprospectivestudyofnormoovulatoryprofessionalathletes
AT herzbergereinathaikin highphysicalactivityandovarianreserveaprospectivestudyofnormoovulatoryprofessionalathletes
AT gluskahadar highphysicalactivityandovarianreserveaprospectivestudyofnormoovulatoryprofessionalathletes
AT dorensteinchen highphysicalactivityandovarianreserveaprospectivestudyofnormoovulatoryprofessionalathletes
AT rahavroni highphysicalactivityandovarianreserveaprospectivestudyofnormoovulatoryprofessionalathletes
AT hemirina highphysicalactivityandovarianreserveaprospectivestudyofnormoovulatoryprofessionalathletes
AT zadanahid highphysicalactivityandovarianreserveaprospectivestudyofnormoovulatoryprofessionalathletes
AT wiseramir highphysicalactivityandovarianreserveaprospectivestudyofnormoovulatoryprofessionalathletes