De novo annotation of lncRNA HOTAIR transcripts by long-read RNA capture-seq reveals a differentiation-driven isoform switch

BACKGROUND: LncRNAs are tissue-specific and emerge as important regulators of various biological processes and as disease biomarkers. HOTAIR is a well-established pro-oncogenic lncRNA which has been attributed a variety of functions in cancer and native contexts. However, a lack of an exhaustive, ce...

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Detalles Bibliográficos
Autores principales: Potolitsyna, Evdokiia, Hazell Pickering, Sarah, Tooming-Klunderud, Ave, Collas, Philippe, Briand, Nolwenn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9482196/
https://www.ncbi.nlm.nih.gov/pubmed/36115964
http://dx.doi.org/10.1186/s12864-022-08887-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9482196/
https://www.ncbi.nlm.nih.gov/pubmed/36115964
http://dx.doi.org/10.1186/s12864-022-08887-w

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