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Probabilistic quotient’s work and pharmacokinetics’ contribution: countering size effect in metabolic time series measurements
Metabolomic time course analyses of biofluids are highly relevant for clinical diagnostics. However, many sampling methods suffer from unknown sample sizes, commonly known as size effects. This prevents absolute quantification of biomarkers. Recently, several mathematical post acquisition normalizat...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9482228/ https://www.ncbi.nlm.nih.gov/pubmed/36114458 http://dx.doi.org/10.1186/s12859-022-04918-1 |