Cargando…

Potential Therapeutic Activity of Berberine in Thyroid-Associated Ophthalmopathy: Inhibitory Effects on Tissue Remodeling in Orbital Fibroblasts

PURPOSE: Berberine (BBR), an alkaloid produced by a traditional Chinese plant, was recently attributed multiple effects on lipometabolism, inflammation, and fibrosis. Thyroid-associated ophthalmopathy (TAO) is highly associated with these pathologic changes. Thus, we aimed to examine the potential t...

Descripción completa

Detalles Bibliográficos
Autores principales:	Diao, Jiale, Chen, Xinxin, Mou, Pei, Ma, Xiaoye, Wei, Ruili
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Association for Research in Vision and Ophthalmology 2022
Materias:	Biochemistry and Molecular Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9482321/ https://www.ncbi.nlm.nih.gov/pubmed/36094643 http://dx.doi.org/10.1167/iovs.63.10.6

Ejemplares similares

Research progress and application of artificial intelligence in thyroid associated ophthalmopathy
por: Diao, Jiale, et al.
Publicado: (2023)

Gypenosides Protect Orbital Fibroblasts in Graves Ophthalmopathy via Anti-Inflammation and Anti-Fibrosis Effects
por: Li, Haoyu, et al.
Publicado: (2020)

Characterization of human tear proteome reveals differentially abundance proteins in thyroid-associated ophthalmopathy
por: Zhou, Xiaoqing, et al.
Publicado: (2022)

Tear proteomics of orbital decompression for disfiguring exophthalmos in inactive thyroid-associated ophthalmopathy
por: Jiang, Lihong, et al.
Publicado: (2020)

The Potential Role of Osteopontin in the Pathogenesis of Graves’ Ophthalmopathy
por: Lou, Heng, et al.
Publicado: (2021)

Characteristics of Hyaluronan Synthesis Inhibition by 4-Methylumbelliferone in Orbital Fibroblasts
por: Galgoczi, Erika, et al.
Publicado: (2020)

Therapeutic Effect of Guggulsterone in Primary Cultured Orbital Fibroblasts Obtained From Patients with Graves’ Orbitopathy
por: Kim, Bo Ram, et al.
Publicado: (2020)

TSHR Signaling Stimulates Proliferation Through PI3K/Akt and Induction of miR-146a and miR-155 in Thyroid Eye Disease Orbital Fibroblasts
por: Woeller, Collynn F., et al.
Publicado: (2019)

Selective BD2 Inhibitor Exerts Anti-Fibrotic Effects via BRD4/FoxM1/Plk1 Axis in Orbital Fibroblasts From Patients With Thyroid Eye Disease
por: Xie, Yanyan, et al.
Publicado: (2023)

Identification and validation of ferroptosis-related genes and immune cell infiltration in thyroid associated ophthalmopathy
por: Chen, Sainan, et al.
Publicado: (2023)

Glycogen Synthase Kinase-3β Mediates Proinflammatory Cytokine Secretion and Adipogenesis in Orbital Fibroblasts from Patients with Graves’ Orbitopathy
por: Lee, Jihei Sara, et al.
Publicado: (2020)

PTX3: A Potential Biomarker in Thyroid Associated Ophthalmopathy
por: Mou, Pei, et al.
Publicado: (2018)

MicroRNA-130a Is Elevated in Thyroid Eye Disease and Increases Lipid Accumulation in Fibroblasts Through the Suppression of AMPK
por: Hammond, Christine L., et al.
Publicado: (2021)

CD34(−) Orbital Fibroblasts From Patients With Thyroid-Associated Ophthalmopathy Modulate TNF-α Expression in CD34(+) Fibroblasts and Fibrocytes
por: Lu, Yan, et al.
Publicado: (2018)

MiRNA-21 promotes fibrosis in orbital fibroblasts from thyroid-associated ophthalmopathy
por: Bo-ding, Tong, et al.
Publicado: (2015)

IL-11 Is Elevated and Drives the Profibrotic Phenotype Transition of Orbital Fibroblasts in Thyroid-Associated Ophthalmopathy
por: Wu, Pengsen, et al.
Publicado: (2022)

The significance of ophthalmological features in diagnosis of thyroid-associated ophthalmopathy
por: Huang, Xiao, et al.
Publicado: (2023)

AURKB Enhances Chromosomal Remodeling of Telomeric Genes and Accelerates Tumorigenesis of Uveal Melanoma
por: Wang, Huixue, et al.
Publicado: (2023)

Chitosan inhibits inflammation and adipogenesis of orbital fibroblasts in Graves ophthalmopathy
por: Xiong, Haibo, et al.
Publicado: (2018)

The Effect of Prostaglandin Analogue Bimatoprost on Thyroid-Associated Orbitopathy
por: Choi, Catherine J., et al.
Publicado: (2018)

The Appearance of the Warburg Effect in the Developing Avian Eye Characterized In Ovo: How Neurogenesis Can Remodel Neuroenergetics
por: Cherix, Antoine, et al.
Publicado: (2020)

Effect of Orbital Decompression on Corneal Topography in Patients with Thyroid Ophthalmopathy
por: Kim, Su Ah, et al.
Publicado: (2015)

Increased response to oxidative stress challenge in Graves’ ophthalmopathy orbital fibroblasts
por: Tsai, Chieh-Chih, et al.
Publicado: (2011)

Inhibitory Effects of α-Lipoic Acid on Oxidative Stress-Induced Adipogenesis in Orbital Fibroblasts From Patients With Graves Ophthalmopathy
por: Hwang, Sena, et al.
Publicado: (2016)

Data on induction of brown/beige adipocytes in mouse retro-orbital adipose tissues
por: Sugiyama, Makoto, et al.
Publicado: (2019)

Autophagy in graves’ ophthalmopathy
por: Chen, Yu-Qing, et al.
Publicado: (2023)

Integrative Analysis of Proteomics and DNA Methylation in Orbital Fibroblasts From Graves’ Ophthalmopathy
por: Virakul, Sita, et al.
Publicado: (2021)

Palmitate induced secretion of IL-6 and MCP-1 in orbital fibroblasts derived from patients with thyroid-associated ophthalmopathy
por: Paik, Ji-Sun, et al.
Publicado: (2012)

Alteration of Connective Tissue Growth Factor (CTGF) Expression in Orbital Fibroblasts from Patients with Graves’ Ophthalmopathy
por: Tsai, Chieh-Chih, et al.
Publicado: (2015)

A Novel Competing Endogenous RNA Network Associated With the Pathogenesis of Graves’ Ophthalmopathy
por: Yue, Zifan, et al.
Publicado: (2021)

Results of diplopia and strabismus in patients with severe thyroid ophthalmopathy after orbital decompression
por: Roncevic, Radmilo, et al.
Publicado: (2014)

Bisphosphonate-Induced Acute Orbital Inflammation in a Patient With Underlying Thyroid Ophthalmopathy
por: Yu, James, et al.
Publicado: (2020)

The outcomes of endoscopic orbital decompression combined with fat decompression for thyroid-associated ophthalmopathy
por: Ye, Yunyan, et al.
Publicado: (2023)

Imaging Evaluation of the Orbit in Graves Ophthalmopathy
por: SAS, T.N., et al.
Publicado: (2015)

Orbital endoscopic decompression in Graves Ophthalmopathy
por: Lima, Wilma Terezinha Anselmo, et al.
Publicado: (2015)

Dihydroartemisinin Exerts Antifibrotic and Anti-Inflammatory Effects in Graves’ Ophthalmopathy by Targeting Orbital Fibroblasts
por: Yang, Shenglan, et al.
Publicado: (2022)

Berberine protects hepatocyte from hypoxia/reoxygenation-induced injury through inhibiting circDNTTIP2
por: Zhu, Yi, et al.
Publicado: (2023)

Data on the inhibitory effect of endophytic fungi of traditional medicinal plants against pancreatic lipase (PL)
por: Patil, Mohini P., et al.
Publicado: (2019)

Fibroblast growth factors as tissue repair and regeneration therapeutics
por: Nunes, Quentin M., et al.
Publicado: (2016)

Thyroid-associated Ophthalmopathy
por: Şahlı, Esra, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_8u7sdh59rc2fgg0b8i53evv84b