Super-enhancer-associated INSM2 regulates lipid metabolism by modulating mTOR signaling pathway in neuroblastoma

BACKGROUND: Abnormal lipid metabolism is one of the most prominent metabolic changes in cancer. Studies have shown that lipid metabolism also plays an important role in neuroblastoma. We recently discovered that the insulinoma-associated 2 gene (INSM2) could regulate lipid metabolism in neuroblastom...

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Detalles Bibliográficos
Autores principales: Cao, Haibo, Zhuo, Ran, Zhang, Zimu, Wang, Jianwei, Tao, Yanfang, Yang, Randong, Guo, Xinyi, Chen, Yanling, Jia, Siqi, Yao, Ye, Yang, Pengcheng, Yu, Juanjuan, Jiao, Wanyan, Li, Xiaolu, Fang, Fang, Xie, Yi, Li, Gen, Wu, Di, Wang, Hairong, Feng, Chenxi, Xu, Yunyun, Li, Zhiheng, Pan, Jian, Wang, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9482322/
https://www.ncbi.nlm.nih.gov/pubmed/36114560
http://dx.doi.org/10.1186/s13578-022-00895-3

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