Cargando…

Focal adhesion kinase-mediated signaling controls the onset of pancreatic cell differentiation

Signals from the endothelium play a pivotal role in pancreatic lineage commitment. As such, the fate of the epithelial cells relies heavily on the spatiotemporal recruitment of the endothelial cells to the embryonic pancreas. Although it is known that VEGFA secreted by the epithelium recruits the en...

Descripción completa

Detalles Bibliográficos
Autores principales:	Rodriguez, Uylissa A., Dahiya, Shakti, Raymond, Michelle L., Gao, Chenxi, Martins-Cargill, Christina P., Piganelli, Jon D., Gittes, George K., Hu, Jing, Esni, Farzad
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Company of Biologists Ltd 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9482336/ https://www.ncbi.nlm.nih.gov/pubmed/36017799 http://dx.doi.org/10.1242/dev.200761

Ejemplares similares

Conversion of α-Cells to β-Cells in the Postpartum Mouse Pancreas Involves Lgr5 Progeny
por: Rodriguez, Uylissa A., et al.
Publicado: (2021)

Neural Cell Adhesion Molecule (N-CAM) Is Required for Cell Type Segregation and Normal Ultrastructure in Pancreatic Islets
por: Esni, Farzad, et al.
Publicado: (1999)

Focal Adhesion Kinases in Adhesion Structures and Disease
por: Eleniste, Pierre P., et al.
Publicado: (2012)

Identification of Newly Committed Pancreatic Cells in the Adult Mouse Pancreas
por: Socorro, Mairobys, et al.
Publicado: (2017)

Targeting Focal Adhesion Kinase Renders Pancreatic Cancers Responsive to Checkpoint Immunotherapy
por: Jiang, Hong, et al.
Publicado: (2016)

Focal adhesion kinase priming in pancreatic cancer, altering biomechanics to improve chemotherapy
por: Murphy, Kendelle J., et al.
Publicado: (2022)

Mechanism of Focal Adhesion Kinase Mechanosensing
por: Zhou, Jing, et al.
Publicado: (2015)

Focal adhesion kinase modulates tension signaling to control actin and focal adhesion dynamics
por: Schober, Markus, et al.
Publicado: (2007)

The KDEL receptor signalling cascade targets focal adhesion kinase on focal adhesions and invadopodia
por: Ruggiero, Carmen, et al.
Publicado: (2017)

Focal adhesion kinase-dependent focal adhesion recruitment of SH2 domains directs SRC into focal adhesions to regulate cell adhesion and migration
por: Wu, Jui-Chung, et al.
Publicado: (2015)

Focal adhesion kinase inhibition synergizes with nab-paclitaxel to target pancreatic ductal adenocarcinoma
por: Le Large, T. Y. S., et al.
Publicado: (2021)

Activation of Rho-kinase and focal adhesion kinase regulates the organization of stress fibers and focal adhesions in the central part of fibroblasts
por: Katoh, Kazuo
Publicado: (2017)

Control of adhesion-dependent cell survival by focal adhesion kinase
Publicado: (1996)

Flotillins Regulate Focal Adhesions by Interacting with α-Actinin and by Influencing the Activation of Focal Adhesion Kinase
por: Banning, Antje, et al.
Publicado: (2018)

Regulation of the Cell Cycle by Focal Adhesion Kinase
por: Zhao, Ji-He, et al.
Publicado: (1998)

Requirement of focal adhesion kinase in branching tubulogenesis
por: Wei, Wei-Chun, et al.
Publicado: (2009)

Emerging Roles of Focal Adhesion Kinase in Cancer
por: Tai, Yu-Ling, et al.
Publicado: (2015)

Targeting focal adhesion kinase in cancer cells and the tumor microenvironment
por: Murphy, James M., et al.
Publicado: (2020)

Focal adhesion kinase a potential therapeutic target for pancreatic cancer and malignant pleural mesothelioma
por: Kanteti, Rajani, et al.
Publicado: (2018)

Targeted Inhibition of Pancreatic Acinar Cell Calcineurin Is a Novel Strategy to Prevent Post-ERCP Pancreatitis
por: Orabi, Abrahim I., et al.
Publicado: (2016)

Identification of sequences required for the efficient localization of the focal adhesion kinase, pp125FAK, to cellular focal adhesions
Publicado: (1993)

Focal Adhesion Remodeling Is Crucial for Glucose-Stimulated Insulin Secretion and Involves Activation of Focal Adhesion Kinase and Paxillin
por: Rondas, Dieter, et al.
Publicado: (2011)

Kinases of the Focal Adhesion Complex Contribute to Cardiomyocyte Specification
por: Robert, Sacha, et al.
Publicado: (2021)

Y‐27632, an Inhibitor of Rho‐associated Protein Kinase, Suppresses Tumor Cell Invasion via Regulation of Focal Adhesion and Focal Adhesion Kinase
por: Imamura, Fumio, et al.
Publicado: (2000)

Regulation of lamellipodial persistence, adhesion turnover, and motility in macrophages by focal adhesion kinase
por: Owen, Katherine A., et al.
Publicado: (2007)

Activation of focal adhesion kinase enhances the adhesion and invasion of pancreatic cancer cells via extracellular signal-regulated kinase-1/2 signaling pathway activation
por: Sawai, Hirozumi, et al.
Publicado: (2005)

Focal Adhesion Kinase Inhibitor Inhibits the Oxidative Damage Induced by Central Venous Catheter via Abolishing Focal Adhesion Kinase-Protein Kinase B Pathway Activation
por: Wang, Yanru, et al.
Publicado: (2021)

Organization and post-transcriptional processing of focal adhesion kinase gene
por: Corsi, Jean-Marc, et al.
Publicado: (2006)

Protein Kinase C, Focal Adhesions and the Regulation of Cell Migration
por: Fogh, Betina S., et al.
Publicado: (2014)

Focal adhesion kinase overexpression and its impact on human osteosarcoma
por: Ren, Ke, et al.
Publicado: (2015)

The Role of Focal Adhesion Kinase in Keratinocyte Fibrogenic Gene Expression
por: Januszyk, Michael, et al.
Publicado: (2017)

Focal adhesion kinase is involved in the migration of human osteosarcoma cells
por: Feng, Sitan, et al.
Publicado: (2021)

Focal adhesion kinase inhibitors, a heavy punch to cancer
por: Wu, Yueling, et al.
Publicado: (2021)

Functional and clinical characteristics of focal adhesion kinases in cancer progression
por: Zhang, Zhaoyu, et al.
Publicado: (2022)

Focal adhesion kinase: from biological functions to therapeutic strategies
por: Tan, Ximin, et al.
Publicado: (2023)

Targeting focal adhesion kinase reprograms the pancreatic tumor microenvironment and renders pancreas cancer responsive to checkpoint immunotherapy
por: Jiang, Hong, et al.
Publicado: (2015)

The extracellular matrix and focal adhesion kinase signaling regulate cancer stem cell function in pancreatic ductal adenocarcinoma
por: Begum, Asma, et al.
Publicado: (2017)

Caspase-mediated Cleavage of Focal Adhesion Kinase pp125(FAK) and Disassembly of Focal Adhesions in Human Endothelial Cell Apoptosis
por: Levkau, Bodo, et al.
Publicado: (1998)

p70S6K is regulated by focal adhesion kinase and is required for Src-selective autophagy
por: Sandilands, Emma, et al.
Publicado: (2015)

Inhibition of focal adhesion kinase enhances antitumor response of radiation therapy in pancreatic cancer through CD8+ T cells
por: Osipov, Arsen, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_of123qq8vnu97e01h4ciu3omve