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Effects of CRISPR/Cas9-mediated stearoyl-Coenzyme A desaturase 1 knockout on mouse embryo development and lipid synthesis

BACKGROUND: Lipid synthesis is an indispensable process during embryo and growth development. Abnormal lipid synthesis metabolism can cause multiple metabolic diseases including obesity and hyperlipidemia. Stearoyl-Coenzyme A desaturase 1 (SCD1) is responsible for catalyzing the synthesis of monouns...

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Detalles Bibliográficos
Autores principales:	Tian, Huibin, Niu, Huimin, Luo, Jun, Yao, Weiwei, Gao, Wenchang, Wen, Yang, Cheng, Min, Lei, Anmin, Hua, Jinlian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	PeerJ Inc. 2022
Materias:	Biochemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9482360/ https://www.ncbi.nlm.nih.gov/pubmed/36124130 http://dx.doi.org/10.7717/peerj.13945

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