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Influence of N-acetyltransferase 2 (NAT2) genotype/single nucleotide polymorphisms on clearance of isoniazid in tuberculosis patients: a systematic review of population pharmacokinetic models

PURPOSE: Significant pharmacokinetic variabilities have been reported for isoniazid across various populations. We aimed to summarize population pharmacokinetic studies of isoniazid in tuberculosis (TB) patients with a specific focus on the influence of N-acetyltransferase 2 (NAT2) genotype/single-n...

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Detalles Bibliográficos
Autores principales:	Thomas, Levin, Raju, Arun Prasath, Chaithra, M, Sonal Sekhar, Varma, Muralidhar, Saravu, Kavitha, Banerjee, Mithu, SV, Chidananda Sanju, Mallayasamy, Surulivelrajan, Rao, Mahadev
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2022
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9482569/ https://www.ncbi.nlm.nih.gov/pubmed/35852584 http://dx.doi.org/10.1007/s00228-022-03362-7

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