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Cancer stem cells induced by chronic stimulation with prostaglandin E2 exhibited constitutively activated PI3K axis

Previously, our group has demonstrated establishment of Cancer Stem Cell (CSC) models from stem cells in the presence of conditioned medium of cancer cell lines. In this study, we tried to identify the factors responsible for the induction of CSCs. Since we found the lipid composition could be trace...

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Detalles Bibliográficos
Autores principales: Minematsu, Hideki, Afify, Said M., Sugihara, Yuki, Hassan, Ghmkin, Zahra, Maram H., Seno, Akimasa, Adachi, Masaki, Seno, Masaharu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9482612/
https://www.ncbi.nlm.nih.gov/pubmed/36115905
http://dx.doi.org/10.1038/s41598-022-19265-7