Single-cell transcriptomics reveal cellular diversity of aortic valve and the immunomodulation by PPARγ during hyperlipidemia

Valvular inflammation triggered by hyperlipidemia has been considered as an important initial process of aortic valve disease; however, cellular and molecular evidence remains unclear. Here, we assess the relationship between plasma lipids and valvular inflammation, and identify association of low-d...

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Autores principales: Lee, Seung Hyun, Kim, Nayoung, Kim, Minkyu, Woo, Sang-Ho, Han, Inhee, Park, Jisu, Kim, Kyeongdae, Park, Kyu Seong, Kim, Kibyeong, Shim, Dahee, Park, Sang-eun, Zhang, Jing Yu, Go, Du-Min, Kim, Dae-Yong, Yoon, Won Kee, Lee, Seung-Pyo, Chung, Jongsuk, Kim, Ki-Wook, Park, Jung Hwan, Lee, Sak, Ann, Soo-jin, Lee, Sang-Hak, Ahn, Hyo-Suk, Jeong, Seong Cheol, Kim, Tae Kyeong, Oh, Goo Taeg, Park, Woong-Yang, Lee, Hae-Ock, Choi, Jae-Hoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9482653/
https://www.ncbi.nlm.nih.gov/pubmed/36115863
http://dx.doi.org/10.1038/s41467-022-33202-2

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