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Regulation of human cortical interneuron development by the chromatin remodeling protein CHD2

Mutations in the chromodomain helicase DNA binding protein 2 (CHD2) gene are associated with neurodevelopmental disorders. However, mechanisms by which CHD2 regulates human brain development remain largely uncharacterized. Here, we used a human embryonic stem cell model of cortical interneuron (hcIN...

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Detalles Bibliográficos
Autores principales: Lewis, E. M. A., Chapman, G., Kaushik, K., Determan, J., Antony, I., Meganathan, K., Narasimhan, M., Gontarz, P., Zhang, B., Kroll, K. L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9482661/
https://www.ncbi.nlm.nih.gov/pubmed/36115870
http://dx.doi.org/10.1038/s41598-022-19654-y