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Human Immune Responses to Plasmodium falciparum infection: Molecular Evidence for a Suboptimal THαβ(TH9) and TH17 Bias over Ideal and Effective Traditional TH1 Immunity

Using microarray analysis, we showed up-regulation of Toll-like receptors 1,2,4,7,8, NF-[kappa][BETA], TNF-[alpha], p38-MAPK and MHC molecules in human peripheral blood mononuclear cells following infection with Plasmodium falciparum. We report herein further studies based on time-course microarray...

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Detalles Bibliográficos
Autores principales: Hu, Wan-Chung(Wan-Jiung), Bourgeois, August Louis, Wolfe, Nathan, Singh, Sher, Jedlicka, Anne, Scott, Alan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9482675/
http://dx.doi.org/10.1038/npre.2011.5930.1