Oral Bacteria Dysbiosis in Patients with Linezolid-Induced Black Hairy Tongue: A Case Series

Linezolid-induced black hairy tongue is a self-limiting benign disease that is rare. Here, we report three patients who developed black hairy tongue after linezolid treatment. The severe dysbiosis of oral bacterial communities was observed in all these patients. Proteobacteria was the most prevalent...

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Autores principales: Shangguan, Yanwan, Ji, Zhongkang, Guo, Wanru, Hu, Wenjuan, Li, Xiaomeng, Xu, Kaijin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Case Series
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9482776/
https://www.ncbi.nlm.nih.gov/pubmed/36128436
http://dx.doi.org/10.2147/IDR.S373266
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author Shangguan, Yanwan
Ji, Zhongkang
Guo, Wanru
Hu, Wenjuan
Li, Xiaomeng
Xu, Kaijin
author_facet Shangguan, Yanwan
Ji, Zhongkang
Guo, Wanru
Hu, Wenjuan
Li, Xiaomeng
Xu, Kaijin
author_sort Shangguan, Yanwan
collection PubMed
description Linezolid-induced black hairy tongue is a self-limiting benign disease that is rare. Here, we report three patients who developed black hairy tongue after linezolid treatment. The severe dysbiosis of oral bacterial communities was observed in all these patients. Proteobacteria was the most prevalent phylum (over 90%) at the black tongue stage. Furthermore, the dramatic oral bacterial alteration took a long time to reverse after the BHT resolved.
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spelling pubmed-94827762022-09-19 Oral Bacteria Dysbiosis in Patients with Linezolid-Induced Black Hairy Tongue: A Case Series Shangguan, Yanwan Ji, Zhongkang Guo, Wanru Hu, Wenjuan Li, Xiaomeng Xu, Kaijin Infect Drug Resist Case Series Linezolid-induced black hairy tongue is a self-limiting benign disease that is rare. Here, we report three patients who developed black hairy tongue after linezolid treatment. The severe dysbiosis of oral bacterial communities was observed in all these patients. Proteobacteria was the most prevalent phylum (over 90%) at the black tongue stage. Furthermore, the dramatic oral bacterial alteration took a long time to reverse after the BHT resolved. Dove 2022-09-14 /pmc/articles/PMC9482776/ /pubmed/36128436 http://dx.doi.org/10.2147/IDR.S373266 Text en © 2022 Shangguan et al. https://creativecommons.org/licenses/by-nc/3.0/This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/ (https://creativecommons.org/licenses/by-nc/3.0/) ). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).
spellingShingle Case Series
Shangguan, Yanwan
Ji, Zhongkang
Guo, Wanru
Hu, Wenjuan
Li, Xiaomeng
Xu, Kaijin
Oral Bacteria Dysbiosis in Patients with Linezolid-Induced Black Hairy Tongue: A Case Series
title Oral Bacteria Dysbiosis in Patients with Linezolid-Induced Black Hairy Tongue: A Case Series
title_full Oral Bacteria Dysbiosis in Patients with Linezolid-Induced Black Hairy Tongue: A Case Series
title_fullStr Oral Bacteria Dysbiosis in Patients with Linezolid-Induced Black Hairy Tongue: A Case Series
title_full_unstemmed Oral Bacteria Dysbiosis in Patients with Linezolid-Induced Black Hairy Tongue: A Case Series
title_short Oral Bacteria Dysbiosis in Patients with Linezolid-Induced Black Hairy Tongue: A Case Series
title_sort oral bacteria dysbiosis in patients with linezolid-induced black hairy tongue: a case series
topic Case Series
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9482776/
https://www.ncbi.nlm.nih.gov/pubmed/36128436
http://dx.doi.org/10.2147/IDR.S373266
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