CTCF acetylation at lysine 20 is required for the early cardiac mesoderm differentiation of embryonic stem cells

The CCCTC-binding factor (CTCF) protein and its modified forms regulate gene expression and genome organization. However, information on CTCF acetylation and its biological function is still lacking. Here, we show that CTCF can be acetylated at lysine 20 (CTCF-K20) by CREB-binding protein (CBP) and...

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Detalles Bibliográficos
Autores principales: Gong, Shixin, Hu, Gongcheng, Guo, Rong, Zhang, Jie, Yang, Yiqi, Ji, Binrui, Li, Gang, Yao, Hongjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Nature Singapore 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9482892/
https://www.ncbi.nlm.nih.gov/pubmed/36117192
http://dx.doi.org/10.1186/s13619-022-00131-w

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