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Extensive Spinal Epidural Abscess Resulting in Complete Paraplegia Treated by Selective Laminectomies and Irrigation

BACKGROUND: Spinal epidural abscess (SEA) is an uncommon clinical entity that is often subject to delayed diagnosis and suboptimal treatment. Untreated disease leads to compression of the spinal cord, resulting in devastating complications. CASE PRESENTATION: A 56‐year‐old man visited our hospital f...

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Autores principales: Xu, Tongshuai, Du, Yukun, Guo, Jianwei, Li, Jianyi, Shao, Cheng, Shi, Changfang, Ren, Xianfeng, Xi, Yongming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons Australia, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9483064/
https://www.ncbi.nlm.nih.gov/pubmed/35732468
http://dx.doi.org/10.1111/os.13367
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author Xu, Tongshuai
Du, Yukun
Guo, Jianwei
Li, Jianyi
Shao, Cheng
Shi, Changfang
Ren, Xianfeng
Xi, Yongming
author_facet Xu, Tongshuai
Du, Yukun
Guo, Jianwei
Li, Jianyi
Shao, Cheng
Shi, Changfang
Ren, Xianfeng
Xi, Yongming
author_sort Xu, Tongshuai
collection PubMed
description BACKGROUND: Spinal epidural abscess (SEA) is an uncommon clinical entity that is often subject to delayed diagnosis and suboptimal treatment. Untreated disease leads to compression of the spinal cord, resulting in devastating complications. CASE PRESENTATION: A 56‐year‐old man visited our hospital for progressive lower back and lower extremity pain of several days' duration. Significant pyrexia (39.5°C) and elevated C‐reactive protein (89.2 mg/L) were detected during admission, but no positive neurological examination findings were observed. Magnetic resonance imaging revealed pyogenic discitis at L3–4. Despite the administration of directed antibiotic therapy, the patient's condition rapidly deteriorated, culminating in complete paraplegia secondary to an extensive SEA from L4 to C7. Emergency spinal decompression surgery was canceled due to his poor clinical condition and refusal of informed consent. After further deterioration, he consented to two‐level selective laminectomies and irrigation. CONCLUSIONS: In contrast with prior case reports, this case illustrates the natural history of an extensive SEA during conservative and late surgical treatment. Early diagnosis and timely surgical decompression are of great importance for extensive SEA.
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spelling pubmed-94830642022-09-29 Extensive Spinal Epidural Abscess Resulting in Complete Paraplegia Treated by Selective Laminectomies and Irrigation Xu, Tongshuai Du, Yukun Guo, Jianwei Li, Jianyi Shao, Cheng Shi, Changfang Ren, Xianfeng Xi, Yongming Orthop Surg Case Reports BACKGROUND: Spinal epidural abscess (SEA) is an uncommon clinical entity that is often subject to delayed diagnosis and suboptimal treatment. Untreated disease leads to compression of the spinal cord, resulting in devastating complications. CASE PRESENTATION: A 56‐year‐old man visited our hospital for progressive lower back and lower extremity pain of several days' duration. Significant pyrexia (39.5°C) and elevated C‐reactive protein (89.2 mg/L) were detected during admission, but no positive neurological examination findings were observed. Magnetic resonance imaging revealed pyogenic discitis at L3–4. Despite the administration of directed antibiotic therapy, the patient's condition rapidly deteriorated, culminating in complete paraplegia secondary to an extensive SEA from L4 to C7. Emergency spinal decompression surgery was canceled due to his poor clinical condition and refusal of informed consent. After further deterioration, he consented to two‐level selective laminectomies and irrigation. CONCLUSIONS: In contrast with prior case reports, this case illustrates the natural history of an extensive SEA during conservative and late surgical treatment. Early diagnosis and timely surgical decompression are of great importance for extensive SEA. John Wiley & Sons Australia, Ltd 2022-06-22 /pmc/articles/PMC9483064/ /pubmed/35732468 http://dx.doi.org/10.1111/os.13367 Text en © 2022 The Authors. Orthopaedic Surgery published by Tianjin Hospital and John Wiley & Sons Australia, Ltd. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Case Reports
Xu, Tongshuai
Du, Yukun
Guo, Jianwei
Li, Jianyi
Shao, Cheng
Shi, Changfang
Ren, Xianfeng
Xi, Yongming
Extensive Spinal Epidural Abscess Resulting in Complete Paraplegia Treated by Selective Laminectomies and Irrigation
title Extensive Spinal Epidural Abscess Resulting in Complete Paraplegia Treated by Selective Laminectomies and Irrigation
title_full Extensive Spinal Epidural Abscess Resulting in Complete Paraplegia Treated by Selective Laminectomies and Irrigation
title_fullStr Extensive Spinal Epidural Abscess Resulting in Complete Paraplegia Treated by Selective Laminectomies and Irrigation
title_full_unstemmed Extensive Spinal Epidural Abscess Resulting in Complete Paraplegia Treated by Selective Laminectomies and Irrigation
title_short Extensive Spinal Epidural Abscess Resulting in Complete Paraplegia Treated by Selective Laminectomies and Irrigation
title_sort extensive spinal epidural abscess resulting in complete paraplegia treated by selective laminectomies and irrigation
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9483064/
https://www.ncbi.nlm.nih.gov/pubmed/35732468
http://dx.doi.org/10.1111/os.13367
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