Intratumoral CD73: An immune checkpoint shaping an inhibitory tumor microenvironment and implicating poor prognosis in Chinese melanoma cohorts

BACKGROUND: As a novel immune checkpoint, CD73 has been reported to play prominent roles in several malignancies. However, the significance of CD73 in melanoma remains ambiguous. This study sought to reveal the impact of CD73 on the tumor microenvironment (TME) and patients’ prognosis, and to invest...

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Detalles Bibliográficos
Autores principales: Gao, Zixu, Wang, Lu, Song, Zhengqing, Ren, Ming, Yang, Yang, Li, Jianrui, Shen, Kangjie, Li, Yinlam, Ding, Yiteng, Yang, Yanwen, Zhou, Yuhong, Wei, Chuanyuan, Gu, Jianying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9483101/
https://www.ncbi.nlm.nih.gov/pubmed/36131912
http://dx.doi.org/10.3389/fimmu.2022.954039

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