The beneficial role of companion animals in translational pain research

The use of spontaneous painful disease in companion pet animals has been highlighted as one of the changes that could be made to help improve translation of basic science to new therapeutics, acting as a bridge between preclinical and clinical studies, with the goal of accelerating the approval of n...

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Autores principales: Lascelles, B. Duncan X., Brown, Dottie C., Conzemius, Michael G., Gill, Marie, Oshinsky, Michael L., Sharkey, Michelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pain Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9483146/
https://www.ncbi.nlm.nih.gov/pubmed/36133153
http://dx.doi.org/10.3389/fpain.2022.1002204
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author Lascelles, B. Duncan X.
Brown, Dottie C.
Conzemius, Michael G.
Gill, Marie
Oshinsky, Michael L.
Sharkey, Michelle
author_facet Lascelles, B. Duncan X.
Brown, Dottie C.
Conzemius, Michael G.
Gill, Marie
Oshinsky, Michael L.
Sharkey, Michelle
author_sort Lascelles, B. Duncan X.
collection PubMed
description The use of spontaneous painful disease in companion pet animals has been highlighted as one of the changes that could be made to help improve translation of basic science to new therapeutics, acting as a bridge between preclinical and clinical studies, with the goal of accelerating the approval of new therapeutics. This review focuses on the utility of companion pet dogs for translational research by reviewing what outcome measures can be measured, and importantly, the relevance of these outcome measures to human translational research. It also details the practical considerations involved in incorporating companion dogs into human therapeutic development.
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spelling pubmed-94831462022-09-20 The beneficial role of companion animals in translational pain research Lascelles, B. Duncan X. Brown, Dottie C. Conzemius, Michael G. Gill, Marie Oshinsky, Michael L. Sharkey, Michelle Front Pain Res (Lausanne) Pain Research The use of spontaneous painful disease in companion pet animals has been highlighted as one of the changes that could be made to help improve translation of basic science to new therapeutics, acting as a bridge between preclinical and clinical studies, with the goal of accelerating the approval of new therapeutics. This review focuses on the utility of companion pet dogs for translational research by reviewing what outcome measures can be measured, and importantly, the relevance of these outcome measures to human translational research. It also details the practical considerations involved in incorporating companion dogs into human therapeutic development. Frontiers Media S.A. 2022-09-05 /pmc/articles/PMC9483146/ /pubmed/36133153 http://dx.doi.org/10.3389/fpain.2022.1002204 Text en © 2022 Lascelles, Brown, Conzemius, Gill, Oshinsky and Sharkey. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY) (https://creativecommons.org/licenses/by/4.0/) . The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Pain Research
Lascelles, B. Duncan X.
Brown, Dottie C.
Conzemius, Michael G.
Gill, Marie
Oshinsky, Michael L.
Sharkey, Michelle
The beneficial role of companion animals in translational pain research
title The beneficial role of companion animals in translational pain research
title_full The beneficial role of companion animals in translational pain research
title_fullStr The beneficial role of companion animals in translational pain research
title_full_unstemmed The beneficial role of companion animals in translational pain research
title_short The beneficial role of companion animals in translational pain research
title_sort beneficial role of companion animals in translational pain research
topic Pain Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9483146/
https://www.ncbi.nlm.nih.gov/pubmed/36133153
http://dx.doi.org/10.3389/fpain.2022.1002204
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